Effect of Laser-Induced Heating on Raman Measurement within a Silicon   Microfluidic Channel

doi:10.3390/mi6070813

CORC > 北京大学 > 软件与微电子学院

	Effect of Laser-Induced Heating on Raman Measurement within a Silicon Microfluidic Channel
	Lin, Ying ; Yu, Xinhai ; Wang, Zhenyu ; Tu, Shan-Tung ; Wang, Zhengdong
刊名	MICROMACHINES
	2015
关键词	CHEMICAL-REACTIONS DEPTH RESOLUTION AXIAL CONDUCTION MICRO-CHANNELS SPECTROSCOPY REFRACTION TEMPERATURE DEVICES SYSTEM
DOI	10.3390/mi6070813
英文摘要	When Raman microscopy is adopted to detect the chemical and biological processes in the silicon microfluidic channel, the laser-induced heating effect will cause a temperature rise in the sample liquid. This undesired temperature rise will mislead the Raman measurement during the temperature-influencing processes. In this paper, computational fluid dynamics simulations were conducted to evaluate the maximum local temperature-rise (MLT). Through the orthogonal analysis, the sensitivity of potential influencing parameters to the MLT was determined. In addition, it was found from transient simulations that it is reasonable to assume the actual measurement to be steady-state. Simulation results were qualitatively validated by experimental data from the Raman measurement of diffusion, a temperature-dependent process. A correlation was proposed for the first time to estimate the MLT. Simple in form and convenient for calculation, this correlation can be efficiently applied to Raman measurement in a silicon microfluidic channel.; China Natural Science Foundation [21176069, 21476073]; Fundamental Research Funds for the Central Universities [WG1213011]; Program for Introduced Talents in Shanghai Institute of Technology [YJ2012-14]; SCI(E); EI; ARTICLE; rememberit@163.com; yxhh@ecust.edu.cn; zw@ss.pku.edu.cn; sttu@ecust.edu.cn; zdwang@ecust.edu.cn; 7; 813-830; 6
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/418807]
专题	软件与微电子学院
推荐引用方式 GB/T 7714	Lin, Ying,Yu, Xinhai,Wang, Zhenyu,et al. Effect of Laser-Induced Heating on Raman Measurement within a Silicon Microfluidic Channel[J]. MICROMACHINES,2015.
APA	Lin, Ying,Yu, Xinhai,Wang, Zhenyu,Tu, Shan-Tung,&Wang, Zhengdong.(2015).Effect of Laser-Induced Heating on Raman Measurement within a Silicon Microfluidic Channel.MICROMACHINES.
MLA	Lin, Ying,et al."Effect of Laser-Induced Heating on Raman Measurement within a Silicon Microfluidic Channel".MICROMACHINES (2015).