Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids

doi:10.1021/acs.langmuir.6b02248

CORC > 北京大学 > 信息科学技术学院

	Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids
	Zhang, Zhenyu ; Wang, Meng ; Gao, Dongliang ; Luo, Da ; Liu, Qinghai ; Yang, Juan ; Li, Yan
刊名	LANGMUIR
	2016
关键词	DRUG-DELIVERY PHOTOTHERMAL THERAPY NANOPARTICLES SCATTERING PLATFORM ACID
DOI	10.1021/acs.langmuir.6b02248
英文摘要	Graphene oxide (GO) is a reliable and multifunctional platform to perform cell imaging. In this work, a controllable Pt-seed-mediated method is used to prepare GO/gold nanoparticle (AuNP) hybrids, and after the covalent binding of folic acid (FA), GO/AuNP/FA hybrids are prepared. Selective labeling and Raman imaging of folate receptor (FR)-positive HeLa cells are realized using such GO based hybrids. In this system, FA is the targeting agent, AuNPs work as surface-enhanced Raman scattering substrates, and GO takes the role of both supporting the AuNPs with FA and acting as a Raman probe. This research further extends the application of GO as a multifunctional platform in bioimaging and other biomedical processes.; National Natural Science Foundation of China [91333105, 21321001]; SCI(E); PubMed; ARTICLE; yanli@pku.edu.cn; 40; 10253-10258; 32
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/492851]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Zhang, Zhenyu,Wang, Meng,Gao, Dongliang,et al. Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids[J]. LANGMUIR,2016.
APA	Zhang, Zhenyu.,Wang, Meng.,Gao, Dongliang.,Luo, Da.,Liu, Qinghai.,...&Li, Yan.(2016).Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids.LANGMUIR.
MLA	Zhang, Zhenyu,et al."Targeted Raman Imaging of Cells Using Graphene Oxide-Based Hybrids".LANGMUIR (2016).