DNA Sequential Logic Gate Using Two-Ring DNA

doi:10.1021/acsami.6b00847

CORC > 北京大学 > 信息科学技术学院

	DNA Sequential Logic Gate Using Two-Ring DNA
	Zhang, Cheng ; Shen, Linjing ; Liang, Chao ; Dong, Yafei ; Yang, Jing ; Xu, Jin
刊名	ACS APPLIED MATERIALS & INTERFACES
	2016
关键词	DNA logic gate sequential detection interlocked structure two-ring DNA gold nanoparticle STRAND-DISPLACEMENT-REACTIONS LABEL-FREE NANOSTRUCTURES CIRCUITS HYBRIDIZATION CONSTRUCTION COMPUTATION DNAZYME DEVICE MOTOR
DOI	10.1021/acsami.6b00847
英文摘要	Sequential DNA detection is a fundamental issue for elucidating the interactive relationships among complex gene systems. Here, a sequential logic DNA gate was achieved by utilizing the two-ring DNA structure, with the ability to recognize "before" and "after" triggering sequences of DNA signals. By taking advantage of a "loop-open" mechanism, separations of two-ring DNAs were controlled. Three triggering pathways with different sequential DNA treatments were distinguished by comparing fluorescent outputs. Programmed nanoparticle arrangement guided by "interlocked" two-ring DNA was also constructed to demonstrate the achievement of designed nanostrucutres. Such sequential logic DNA operation may guide future molecular sensors to monitor more complex gene network in biological systems.; National Natural Science Foundation of China [61272161, 61370099, 61425002, 61472333, 61320106005, 61572046]; SCI(E); EI; PubMed; ARTICLE; zhangcheng369@pku.edu.cn; yjzcdd_2000@ncepu.edu.cn; jxu@pku.edu.cn; 14; 9370-9376; 8
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/434457]
专题	信息科学技术学院
推荐引用方式 GB/T 7714	Zhang, Cheng,Shen, Linjing,Liang, Chao,et al. DNA Sequential Logic Gate Using Two-Ring DNA[J]. ACS APPLIED MATERIALS & INTERFACES,2016.
APA	Zhang, Cheng,Shen, Linjing,Liang, Chao,Dong, Yafei,Yang, Jing,&Xu, Jin.(2016).DNA Sequential Logic Gate Using Two-Ring DNA.ACS APPLIED MATERIALS & INTERFACES.
MLA	Zhang, Cheng,et al."DNA Sequential Logic Gate Using Two-Ring DNA".ACS APPLIED MATERIALS & INTERFACES (2016).