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	Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making
	Li, Nan ; Ma, Ning ; Liu, Ying ; He, Xiao-Song ; Sun, De-Lin ; Fu, Xian-Ming ; Zhang, Xiaochu ; Han, Shihui ; Zhang, Da-Ren
刊名	journal of neuroscience
	2013
关键词	PREFRONTAL CORTEX INTERTEMPORAL CHOICE REGRESSION-ANALYSIS NEURAL MECHANISMS IMMEDIATE REWARD DELAYED REWARDS ANTERIOR INSULA FRONTAL-CORTEX HUMAN BRAIN NETWORKS
DOI	10.1523/JNEUROSCI.1342-12.2013
英文摘要	Increasing neuroimaging evidence suggests an association between impulsive decision-making behavior and task-related brain activity. However, the relationship between impulsivity in decision-making and resting-state brain activity remains unknown. To address this issue, we used functional MRI to record brain activity from human adults during a resting state and during a delay discounting task (DDT) that requires choosing between an immediate smaller reward and a larger delayed reward. In experiment I, we identified four DDT related brain networks. The money network (the striatum, posterior cingulate cortex, etc.) and the time network (the medial and dorsolateral prefrontal cortices, etc.) were associated with the valuation process; the frontoparietal network and the dorsal anterior cingulate cortex-anterior insular cortex network were related to the choice process. Moreover, we found that the resting-state functional connectivity of the brain regions in these networks was significantly correlated with participants' discounting rate, a behavioral index of impulsivity during the DDT. In experiment II, we tested an independent group of subjects and demonstrated that this resting-state functional connectivity was able to predict individuals' discounting rates. Together, these findings suggest that resting-state functional organization of the human brain may be a biomarker of impulsivity and can predict economic decision-making behavior.; Neurosciences; SCI(E); SSCI; 11; ARTICLE; 11; 4886-4895; 33
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/391999]
专题	心理与认知科学学院
推荐引用方式 GB/T 7714	Li, Nan,Ma, Ning,Liu, Ying,et al. Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making[J]. journal of neuroscience,2013.
APA	Li, Nan.,Ma, Ning.,Liu, Ying.,He, Xiao-Song.,Sun, De-Lin.,...&Zhang, Da-Ren.(2013).Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making.journal of neuroscience.
MLA	Li, Nan,et al."Resting-State Functional Connectivity Predicts Impulsivity in Economic Decision-Making".journal of neuroscience (2013).

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