中国地下水砷健康风险评价

CORC > 北京大学 > 城市与环境学院

	中国地下水砷健康风险评价; Health risk assessment of arsenic in groundwater across China
	邓安琪 ; 董兆敏 ; 高群 ; 胡建英
刊名	中国环境科学
	2017
关键词	地下水砷风险评价皮肤癌膀胱癌肺癌 groundwater arsenic risk assessment skin cancer bladder cancer lung cancer
英文摘要	以皮肤癌、膀胱癌、肺癌及联合毒性(膀胱癌和肺癌联合)为毒性终点,结合我国地下水砷浓度分布,评价了我国人群暴露于地下水砷的健康风险.研究表明我国各地地下水砷浓度几何均值为1.597~6.216μg/L,经面积校正后,全国地下水砷浓度几何均值为2.773μg/L.计算表明,我国男性人群日均暴露量几何均值为0.088μg/(kg bw·d),女性人群日均暴露量几何均值为0.093μg/(kg bw·d).基于此,全国男性由地下水中砷暴露带来的皮肤癌、肺癌、膀胱癌风险期望值分别为1.32×10-4,5.88×10-4和9.83×10-4,男性膀胱癌和肺癌的联合风险期望值为1.48×10-3;全国女性由地下水中砷暴露引起的皮肤癌、肺癌和膀胱癌风险期望值分别为1.35×10-4,1.49×10-3和9.42×10-4,女性膀胱癌和肺癌的联合风险期望值为2.31×10-3,女性风险均高于男性.大部分地区皮肤癌致癌风险在饮用水砷可接受风险水平10-4范围之内,而大部分肺癌、膀胱癌及其联合致癌风险值均超出了可接受风险水平.; The health human risk of inorganic arsenic (As) in groundwater was assessed usingthe skin cancer, bladder cancer, lung cancer and the union of bladder cancer and lung cancer were selected as the endpoints. The geometric mean (GM) of arsenic concentrations in groundwater across China was estimated to be in the range of 1.597~6.216μg/L. After adjusting area of each province, the GM of As was 2.773μg/L. The average daily dose (ADDs) for maleand female of As via intake of underground water were estimated to be 0.088μg/(kg bw·d) and 0.093μg/(kg bw·d), respectively. Thus, the expected risk for male raised by As via groundwater exposure was calculated to be 1.32×10-4 for skin cancer, 9.83×10-4 for bladdercancer, 5.88×10-4for lung cancer, and 1.48× 10-3for joint cancer risk (bladder cancer and lung cancer). The cancer risk for female was 1.35×10-4, 9.42×10-4, 1.49×10-3, and 2.31×10-3 for skin, bladder, lung and the joint cancer risk, respectively, higher than those for male. In most provinces, the risk is higher than the acceptable risk level of 10-4 for As set by US EPA.; 保障饮用水安全的高通量毒性物质甄别技术; 国家水专项; 9; 3556-3565; 37
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/463372]
专题	城市与环境学院
推荐引用方式 GB/T 7714	邓安琪,董兆敏,高群,等. 中国地下水砷健康风险评价, Health risk assessment of arsenic in groundwater across China[J]. 中国环境科学,2017.
APA	邓安琪,董兆敏,高群,&胡建英.(2017).中国地下水砷健康风险评价.中国环境科学.
MLA	邓安琪,et al."中国地下水砷健康风险评价".中国环境科学 (2017).