Transformation of tetracycline during chloramination: Kinetics, products   and pathways

doi:10.1016/j.chemosphere.2012.09.001

CORC > 北京大学 > 城市与环境学院

	Transformation of tetracycline during chloramination: Kinetics, products and pathways
	Wan, Yi ; Jia, Ai ; Zhu, Zhou ; Hu, Jianying
刊名	chemosphere
	2013
关键词	Tetracycline Chloramine Chlorination Growth inhibition toxicity Sludge bacteria TANDEM MASS-SPECTROMETRY WATER TREATMENT PLANTS RESISTANCE GENES WASTE-WATER LIQUID-CHROMATOGRAPHY ANTIBACTERIAL AGENTS DEGRADATION-PRODUCTS AQUATIC ENVIRONMENT CHLORINATION BACTERIA
DOI	10.1016/j.chemosphere.2012.09.001
英文摘要	To assess the potential adverse effects stemming from tetracycline (TC) in drinking water or disinfected wastewater, the kinetics of the chloramination of TC was investigated at room temperature, the transformation products and pathways of their generation were elucidated, and their growth inhibiting properties towards sludge bacteria were assessed. The chloramination of TC exhibited pseudo-first-order kinetics with the rate constants (k(obs)) ranging from 0.0082 to 0.041 min(-1) at pH of 6-8. Chloramination of TC generated at least 13 discernible products, and the structures of 12 products, including five chlorinated compounds, were identified using LC-ESI-MS. Two main pathways for the generation of these products were proposed: (1) chlorine substitution reactions followed by dehydration; and (2) oxidization by chloramine. The chlorinated products were proposed to be further degraded to small molecules via the scission of benzene rings of TC, and two oxidization products (2,11a-dihydroxy-keto-TC and 6,11-epoxy-2,11a-dihydroxy-TC) were the final products obtained under the experimental conditions. The chlorinated solution, even without detection of TC, exhibited greater than 80% of TC inhibitory effects towards sludge bacteria, suggesting potential effects on microorganisms in aquatic environment. (C) 2012 Elsevier Ltd. All rights reserved.; Environmental Sciences; SCI(E); EI; PubMed; 2; ARTICLE; 4; 1427-1434; 90
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/160631]
专题	城市与环境学院
推荐引用方式 GB/T 7714	Wan, Yi,Jia, Ai,Zhu, Zhou,et al. Transformation of tetracycline during chloramination: Kinetics, products and pathways[J]. chemosphere,2013.
APA	Wan, Yi,Jia, Ai,Zhu, Zhou,&Hu, Jianying.(2013).Transformation of tetracycline during chloramination: Kinetics, products and pathways.chemosphere.
MLA	Wan, Yi,et al."Transformation of tetracycline during chloramination: Kinetics, products and pathways".chemosphere (2013).