Genome-wide study of an elite rice pedigree reveals a complex history of   genetic architecture for breeding improvement

doi:10.1038/srep45685

CORC > 北京大学 > 生命科学学院

	Genome-wide study of an elite rice pedigree reveals a complex history of genetic architecture for breeding improvement
	Chen, Shaoxia ; Lin, Zechuan ; Zhou, Degui ; Wang, Chongrong ; Li, Hong ; Yu, Renbo ; Deng, Hanchao ; Tang, Xiaoyan ; Zhou, Shaochuan ; Deng, Xing Wang ; He, Hang
刊名	SCIENTIFIC REPORTS
	2017
关键词	ORYZA-SATIVA L. ARTIFICIAL SELECTION MOLECULAR-GENETICS RESISTANCE GENES GRAIN WIDTH ASSOCIATION POLYMORPHISM STARCH OVEREXPRESSION SIMULATION
DOI	10.1038/srep45685
英文摘要	Improving breeding has been widely utilized in crop breeding and contributed to yield and quality improvement, yet few researches have been done to analyze genetic architecture underlying breeding improvement comprehensively. Here, we collected genotype and phenotype data of 99 cultivars from the complete pedigree including Huanghuazhan, an elite, high-quality, conventional indica rice that has been grown over 4.5 million hectares in southern China and from which more than 20 excellent cultivars have been derived. We identified 1,313 selective sweeps (SSWs) revealing four stage-specific selection patterns corresponding to improvement preference during 65 years, and 1113 conserved Huanghuazhan traceable blocks (cHTBs) introduced from different donors and conserved in > 3 breeding generations were the core genomic regions for superior performance of Huanghuazhan. Based on 151 quantitative trait loci (QTLs) identified for 13 improved traits in the pedigree, we reproduced their improvement process in silico, highlighting improving breeding works well for traits controlled by major/major + minor effect QTLs, but was inefficient for traits controlled by QTLs with complex interactions or explaining low levels of phenotypic variation. These results indicate long-term breeding improvement is efficient to construct superior genetic architecture for elite performance, yet molecular breeding with designed genotype of QTLs can facilitate complex traits improvement.; National Program on Key Basic Research Project of China (973 Program) [2013CBA01402]; National High Technology Research and Development Program of China (863 Program) [2012AA10A304, 2014AA10A602]; National Natural Science Foundation of China [U1031001, 31201277]; SCI(E); ARTICLE; 7
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/474099]
专题	生命科学学院
推荐引用方式 GB/T 7714	Chen, Shaoxia,Lin, Zechuan,Zhou, Degui,et al. Genome-wide study of an elite rice pedigree reveals a complex history of genetic architecture for breeding improvement[J]. SCIENTIFIC REPORTS,2017.
APA	Chen, Shaoxia.,Lin, Zechuan.,Zhou, Degui.,Wang, Chongrong.,Li, Hong.,...&He, Hang.(2017).Genome-wide study of an elite rice pedigree reveals a complex history of genetic architecture for breeding improvement.SCIENTIFIC REPORTS.
MLA	Chen, Shaoxia,et al."Genome-wide study of an elite rice pedigree reveals a complex history of genetic architecture for breeding improvement".SCIENTIFIC REPORTS (2017).