Pathways for Epidermal Cell Differentiation via the Homeobox Gene GLABRA2: Update on the Roles of the Classic Regulator

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	Pathways for Epidermal Cell Differentiation via the Homeobox Gene GLABRA2: Update on the Roles of the Classic Regulator
	Qing Lin ; Aoyama Takashi
刊名	Journal of Integrative Plant Biology
	2012
关键词	Morphogenesis pattern formation root hair trichome transcription factor
英文摘要	Recent plant development studies have identified regulatory pathways for epidermal cell differentiation in Arabidopsis thaliana. Interestingly, some of such pathways contain transcriptional networks with a common structure in which the homeobox gene GLABLA2 (GL2) is downstream of the transactivation complex consisting of MYB, bHLH, and WD40 proteins. Here, we review the role of GL2 as an output device of the conserved network, and update the knowledge of epidermal cell differentiation pathways downstream of GL2. Despite the consistent position of GL2 within the network, its role in epidermal tissues varies; in the root epidermis, GL2 promotes non-hair cell differentiation after cell pattern formation, whereas in the leaf epidermis, it is likely to be involved in both pattern formation and differentiation of trichomes. GL2 expression levels act as quantitative factors for initiation of cell differentiation in the root and leaf epidermis; the quantity of hairless cells in non-root hair cell files is reduced by g/2 mutations in a semi-dominant manner, and entopically additive expression of GL2 and a heterozygous g12 mutation increase and decrease the number of trichomes, respectively. Although few direct target genes have been identified, evidence from genetic and expression analyses suggests that GL2 directly regulates genes with various hierarchies in epidermal cell differentiation pathways.; the Japan-China Joint Research Projects/Seminars between JSPS,the National Natural Science Foundation of China; 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); 10; 729-737; 54
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/462142]
专题	生命科学学院
推荐引用方式 GB/T 7714	Qing Lin,Aoyama Takashi. Pathways for Epidermal Cell Differentiation via the Homeobox Gene GLABRA2: Update on the Roles of the Classic Regulator[J]. Journal of Integrative Plant Biology,2012.
APA	Qing Lin,&Aoyama Takashi.(2012).Pathways for Epidermal Cell Differentiation via the Homeobox Gene GLABRA2: Update on the Roles of the Classic Regulator.Journal of Integrative Plant Biology.
MLA	Qing Lin,et al."Pathways for Epidermal Cell Differentiation via the Homeobox Gene GLABRA2: Update on the Roles of the Classic Regulator".Journal of Integrative Plant Biology (2012).