DELLA proteins interact with FLC to repress flowering transition

doi:10.1111/jipb.12451

CORC > 北京大学 > 生命科学学院

	DELLA proteins interact with FLC to repress flowering transition
	Li, Mingzhe ; An, Fengying ; Li, Wenyang ; Ma, Mengdi ; Feng, Ying ; Zhang, Xing ; Guo, Hongwei
刊名	JOURNAL OF INTEGRATIVE PLANT BIOLOGY
	2016
关键词	Arabidopsis co-repressor DELLAs FLC flowering E3 UBIQUITIN LIGASE ARABIDOPSIS-THALIANA COORDINATED REGULATION ANTISENSE TRANSCRIPTS TRANSIENT EXPRESSION FUNCTIONAL-ANALYSIS NONCODING RNA INTEGRATOR FT PLANT-GROWTH DNA-BINDING
DOI	10.1111/jipb.12451
英文摘要	Flowering is a highly orchestrated and extremely critical process in a plant's life cycle. Previous study has demonstrated that SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) and FLOWERING LOCUS T (FT) integrate the gibberellic acid (GA) signaling pathway and vernalization pathway in regulating flowering time, but detailed molecular mechanisms remain largely unclear. In GA signaling pathway, DELLA proteins are a group of master transcriptional regulators, while in vernalization pathway FLOWERING LOCUS C (FLC) is a core transcriptional repressor that down-regulates the expression of SOC1 and FT. Here, we report that DELLA proteins interact with FLC in vitro and in vivo, and the LHRI domains of DELLAs and the C-terminus of MADS domain of FLC are required for these interactions. Phenotypic and gene expression analysis showed that mutation of FLC reduces while over-expression of FLC enhances the GA response in the flowering process. Further, DELLA-FLC interactions promote the repression ability of FLC on its target genes. In summary, these findings report that the interaction between MADS box transcription factor FLC and GRAS domain regulator DELLAs may integrate various signaling inputs in flowering time control, and shed new light on the regulatory mechanism both for FLC and DELLAs in regulating gene expression.; grants from the National Natural Science Foundation of China; Ministry of Agriculture of China (2010ZX08010-002). The publication fee is covered by the 111 project of Peking University; SCI(E); PubMed; 中国科技核心期刊(ISTIC); 中国科学引文数据库(CSCD); ARTICLE; fyan1204@gmail.com; hongweig@pku.edu.cn; 7; 642-655; 58
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/416658]
专题	生命科学学院
推荐引用方式 GB/T 7714	Li, Mingzhe,An, Fengying,Li, Wenyang,et al. DELLA proteins interact with FLC to repress flowering transition[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2016.
APA	Li, Mingzhe.,An, Fengying.,Li, Wenyang.,Ma, Mengdi.,Feng, Ying.,...&Guo, Hongwei.(2016).DELLA proteins interact with FLC to repress flowering transition.JOURNAL OF INTEGRATIVE PLANT BIOLOGY.
MLA	Li, Mingzhe,et al."DELLA proteins interact with FLC to repress flowering transition".JOURNAL OF INTEGRATIVE PLANT BIOLOGY (2016).