Misbinding of Color and Motion in Human Visual Cortex

doi:10.1016/j.cub.2014.04.045

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	Misbinding of Color and Motion in Human Visual Cortex
	Zhang, Xilin ; Qiu, Jiang ; Zhang, Yanyu ; Han, Shihui ; Fang, Fang
刊名	current biology
	2014
关键词	BINDING PROBLEM ILLUSORY CONJUNCTIONS AREA V2 PERCEPTION REENTRY FORM V1
DOI	10.1016/j.cub.2014.04.045
英文摘要	A fundamental challenge for the visual system is to integrate visual features into a coherent scene, known as the binding problem. The neural mechanisms of feature binding are hard to identify because of difficulties in separating active feature binding from feature co-occurrence. In previous studies on feature binding [1-5], visual features were superimposed and presented simultaneously. Neurons throughout the visual cortex are known to code multiple features [6]. Therefore, the observed binding effects could be due to the physical co-occurrence of features and the sensory representation of feature pairings. It is uncertain whether the mechanisms responsible for perceptual binding were actually recruited [7, 8]. To address this issue, we performed psychophysical and fMRI experiments to investigate the neural mechanisms of a steady-state misbinding of color and motion [9], because feature misbinding is probably the most striking evidence for the active existence of the binding mechanisms [10]. We found that adapting to the color-motion misbinding generated the color-contingent motion aftereffect, as well as the color-contingent motion adaptation effect in visual cortex. Notably, V2 exhibited the strongest adaptation effect, which significantly correlated with the aftereffect across subjects. Furthermore, effective connectivity analysis using dynamic causal modeling showed that the misbinding was closely associated with enhanced feedback from V4 and V5 to V2. These findings provide strong evidence for active feature binding in early visual cortex and suggest a critical role of reentrant connections from specialized intermediate areas to early visual cortex in this process.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337648200025&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemistry & Molecular Biology; Cell Biology; SCI(E); PubMed; 1; ARTICLE; ffang@pku.edu.cn; 12; 1354-1360; 24
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/162734]
专题	生命科学学院心理与认知科学学院
推荐引用方式 GB/T 7714	Zhang, Xilin,Qiu, Jiang,Zhang, Yanyu,et al. Misbinding of Color and Motion in Human Visual Cortex[J]. current biology,2014.
APA	Zhang, Xilin,Qiu, Jiang,Zhang, Yanyu,Han, Shihui,&Fang, Fang.(2014).Misbinding of Color and Motion in Human Visual Cortex.current biology.
MLA	Zhang, Xilin,et al."Misbinding of Color and Motion in Human Visual Cortex".current biology (2014).