Biomimetic Nanofluidic Diode Composed of Dual Amphoteric Channels   Maintains Rectification Direction over a Wide pH Range

doi:10.1002/anie.201606469

CORC > 北京大学 > 化学与分子工程学院

	Biomimetic Nanofluidic Diode Composed of Dual Amphoteric Channels Maintains Rectification Direction over a Wide pH Range
	Sui, Xin ; Zhang, Zhen ; Zhang, Zhenyu ; Wang, Zhiwei ; Li, Chao ; Yuan, Hao ; Gao, Longcheng ; Wen, Liping ; Fan, Xia ; Yang, Lijun ; Zhang, Xinru ; Jiang, Lei
刊名	ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
	2016
关键词	amphoteric nanochannels block copolymers ion transport nanofluidic diodes ph-gating NANOPOROUS THIN-FILMS SOLID-STATE NANOPORES BLOCK-COPOLYMER TRIBLOCK COPOLYMERS NANOCHANNEL MEMBRANES POLYMER NANOSTRUCTURES DERIVATIVES NANOTUBES
DOI	10.1002/anie.201606469
英文摘要	pH-gated ion channels in cell membranes play important roles in the cell's physiological activities. Many artificial nanochannels have been fabricated to mimic the natural phenomenon of pH-gated ion transport. However, these nanochannels show pH sensitivity only within certain pH ranges. Wide-range pH sensitivity has not yet been achieved. Herein, for the first time, we provide a versatile strategy to increase the pH-sensitive range by using dual amphoteric nanochannels. In particular, amphoteric polymeric nanochannels with carboxyl groups derived from a block copolymer (BCP) precursor and nanochannels with hydroxyl groups made from anodic alumina oxide (AAO) were used. Due to a synergistic effect, the hybrid nanochannels exhibit nanofluidic diode properties with single rectification direction over awide pH range. The novel strategy presented here is a scalable, low-cost, and robust alternative for the construction of large-area membranes for nanofluidic applications, such as the separation of biomolecules.; National Natural Science Foundation [21434003, 91427303, 51673206, 21204002]; SCI(E); PubMed; ARTICLE; lcgao@buaa.edu.cn; wen@mail.ipc.ac.cn; fanxia@buaa.edu.cn; 42; 13056-13060; 55
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/492737]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Sui, Xin,Zhang, Zhen,Zhang, Zhenyu,et al. Biomimetic Nanofluidic Diode Composed of Dual Amphoteric Channels Maintains Rectification Direction over a Wide pH Range[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2016.
APA	Sui, Xin.,Zhang, Zhen.,Zhang, Zhenyu.,Wang, Zhiwei.,Li, Chao.,...&Jiang, Lei.(2016).Biomimetic Nanofluidic Diode Composed of Dual Amphoteric Channels Maintains Rectification Direction over a Wide pH Range.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.
MLA	Sui, Xin,et al."Biomimetic Nanofluidic Diode Composed of Dual Amphoteric Channels Maintains Rectification Direction over a Wide pH Range".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016).