Electron Crystallography Reveals Atomic Structures of Metal-Organic   Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf)   Secondary Building Units

doi:10.1021/acs.inorgchem.7b00845

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	Electron Crystallography Reveals Atomic Structures of Metal-Organic Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) Secondary Building Units
	Dai, Ruihan ; Peng, Fei ; Ji, Pengfei ; Lu, Kuangda ; Wang, Cheng ; Sun, Junhang ; Lin, Wenbin
刊名	INORGANIC CHEMISTRY
	2017
关键词	DRUG-DELIVERY PHOTODYNAMIC THERAPY LIVE CELLS FRAMEWORKS CATALYSTS CARRIERS NANO
DOI	10.1021/acs.inorgchem.7b00845
英文摘要	Nanoscale metal organic frameworks (nMOFs) have shown tremendous potential in cancer therapy and biomedical imaging. However, their small dimensions present a significant challenge in structure determination by single-crystal X-ray crystallography. We report here the structural determination of nMOFs by rotation electron diffraction (RED). Two isostructural Zr- and Hf-based nMOFs with linear biphenyldicarboxylate (BPDC) or bipyridinedicarboxylate (BPYDC) linkers are stable under intense electron beams to allow the collection of high-quality RED data, which reveal a MOF structure with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) secondary building units (SBUs). The nMOF structures differ significantly from their UiO bulk counterparts with M-6(mu(3)-O)(4)(mu(3)-OH)(4) SBUs and provide the foundation for clarifying the structures of a series of previously reported nMOFs with significant potential in cancer therapy and biological imaging. Our work clearly demonstrates the power of RED in determining nMOF structures and elucidating the formation mechanism of distinct nMOF morphologies.; National Natural Science Foundation; Ministry of Science and Technology of the People's Republic of China [NSFC21671162, NSFC21471126, 2016YFA0200702]; National Thousand Talents Program of the People's Republic of China; 985 Program of Chemistry and Chemical Engineering Disciplines of Xiamen University; U.S. National Science Foundation [DMR-1308229]; SCI(E); ARTICLE; 14; 8128-8134; 56
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/472108]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Dai, Ruihan,Peng, Fei,Ji, Pengfei,et al. Electron Crystallography Reveals Atomic Structures of Metal-Organic Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) Secondary Building Units[J]. INORGANIC CHEMISTRY,2017.
APA	Dai, Ruihan.,Peng, Fei.,Ji, Pengfei.,Lu, Kuangda.,Wang, Cheng.,...&Lin, Wenbin.(2017).Electron Crystallography Reveals Atomic Structures of Metal-Organic Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) Secondary Building Units.INORGANIC CHEMISTRY.
MLA	Dai, Ruihan,et al."Electron Crystallography Reveals Atomic Structures of Metal-Organic Nanoplates with M-12(mu(3)-O)(8)(mu(3)-OH)(8)(mu(2)-OH)(6) (M = Zr, Hf) Secondary Building Units".INORGANIC CHEMISTRY (2017).