Mechanistic Considerations of the Catalytic Guanylation Reaction of   Amines with Carbodiimides for Guanidine Synthesis

doi:10.1021/acs.organomet.5b00251

CORC > 北京大学 > 化学与分子工程学院

	Mechanistic Considerations of the Catalytic Guanylation Reaction of Amines with Carbodiimides for Guanidine Synthesis
	Xu, Ling ; Zhang, Wen-Xiong ; Xi, Zhenfeng
刊名	ORGANOMETALLICS
	2015
关键词	EARTH-METAL COMPLEXES N BOND FORMATION EFFICIENT MULTICOMPONENT REACTIONS C-N SUBSTITUTED GUANIDINES H BONDS BENZIMIDAZOLE DERIVATIVES COORDINATION CHEMISTRY LANTHANIDE COMPLEXES ENYNE-CARBODIIMIDES
DOI	10.1021/acs.organomet.5b00251
英文摘要	Catalytic guanylation reactions of amines with carbodiimides have received increasing attention because of the atom-economical preparation of guanidines since 2003. To date, more than 40 catalysts including transition metals, main-group metals, and rare-earth metals have been designed and tested for the guanylation reaction to construct acyclic and cyclic guanidines. In this review, we present a mechanistic consideration on catalytic guanylation reactions of amines with carbodiimides for guanidine synthesis to elucidate its development and importance. Four different types of reaction mechanisms have been well categorized: [2 + 2]-cydoaddition/protonation, insertion/protonation, activation of carbodiimide/nudeophilic addition/intramolecular protonation, and protonation/nucleophilic addition/disassociation. It is useful to understand these reaction processes in order to accelerate the rapid development in related areas to meet the growing need for guanidines.; Natural Science Foundation of China; "973" program from the National Basic Research Program of China [2011CB808601]; SCI(E); EI; ARTICLE; wx_zhang@pku.edu.cn; 10; 1787-1801; 34
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/419935]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xu, Ling,Zhang, Wen-Xiong,Xi, Zhenfeng. Mechanistic Considerations of the Catalytic Guanylation Reaction of Amines with Carbodiimides for Guanidine Synthesis[J]. ORGANOMETALLICS,2015.
APA	Xu, Ling,Zhang, Wen-Xiong,&Xi, Zhenfeng.(2015).Mechanistic Considerations of the Catalytic Guanylation Reaction of Amines with Carbodiimides for Guanidine Synthesis.ORGANOMETALLICS.
MLA	Xu, Ling,et al."Mechanistic Considerations of the Catalytic Guanylation Reaction of Amines with Carbodiimides for Guanidine Synthesis".ORGANOMETALLICS (2015).