Direct construction of vicinal all-carbon quaternary stereocenters in   natural product synthesis

doi:10.1039/c5np00046g

CORC > 北京大学 > 化学与分子工程学院

	Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis
	Long, Rong ; Huang, Jun ; Gong, Jianxian ; Yang, Zhen
刊名	NATURAL PRODUCT REPORTS
	2015
关键词	ARENE-OLEFIN CYCLOADDITIONS ASYMMETRIC TOTAL-SYNTHESIS CONCISE TOTAL-SYNTHESIS DIELS-ALDER REACTION ENANTIOSELECTIVE CLAISEN REARRANGEMENTS DAPHNIPHYLLUM ALKALOIDS CALYCANTHACEOUS ALKALOIDS STEREOSELECTIVE-SYNTHESIS NAZAROV CYCLIZATION MESO-CHIMONANTHINE
DOI	10.1039/c5np00046g
英文摘要	Molecules containing vicinal all-carbon quaternary stereocenters are found in many secondary metabolites, and they exhibit a variety of biological and pharmacological activities. However, the construction of such a structural motif remains a significant challenge in natural product synthesis. Only in recent years have considerable efforts been made to construct vicinal quaternary stereocenters in a single-step operation. In this review, we focus on the different types of methods that have been successfully used in the total synthesis of natural products. Based on the classified reactions for the simultaneous generation of vicinal all-carbon quaternary stereocenters, the total syntheses of the natural products are discussed, placing emphasis on the diastereoselective preparation of vicinal quaternary carbon centers and the subsequent total syntheses.; SCI(E); PubMed; REVIEW; zyang@pku.edu.cn; 11; 1584-1601; 32
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/418213]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Long, Rong,Huang, Jun,Gong, Jianxian,et al. Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis[J]. NATURAL PRODUCT REPORTS,2015.
APA	Long, Rong,Huang, Jun,Gong, Jianxian,&Yang, Zhen.(2015).Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis.NATURAL PRODUCT REPORTS.
MLA	Long, Rong,et al."Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis".NATURAL PRODUCT REPORTS (2015).