Palladium-Catalyzed Oxidative Cross-Coupling of Conjugated Enynones with   Organoboronic Acids

doi:10.1021/acs.joc.5b01350

CORC > 北京大学 > 化学与分子工程学院

	Palladium-Catalyzed Oxidative Cross-Coupling of Conjugated Enynones with Organoboronic Acids
	Xia, Ying ; Ge, Rui ; Chen, Li ; Liu, Zhen ; Xiao, Qing ; Zhang, Yan ; Wang, Jianbo
刊名	JOURNAL OF ORGANIC CHEMISTRY
	2015
关键词	CARBENE MIGRATORY INSERTION ENE-YNE-KETONES OXIDATION/1,2-ALKYNYL MIGRATION/CYCLIZATION CASCADE C-BOND FORMATION N-TOSYLHYDRAZONES TERMINAL ALKYNES (2-FURYL)CARBENE COMPLEXES SUBSTITUTED FURANS ALLENYL KETONES DIAZO-COMPOUNDS
DOI	10.1021/acs.joc.5b01350
英文摘要	A palladium-catalyzed oxidative cross-coupling reaction of conjugated enynones with organoboronic acids is developed. This reaction provides an efficient methodology for the synthesis of functionalized furan derivatives, including 2-alkenylfurans and furan-substituted 1,3-dienes. Palladium-carbene migratory insertion is proposed as the key step in these transformations. Notably, the beta-hydride elimination process occurs in a stereoselective manner, resulting in the formation of double bonds with high (E)-selectivity.; National Basic Research Program of China (973 Program) [2012CB821600]; Natural Science Foundation of China [21472004, 21332002]; SCI(E); EI; PubMed; ARTICLE; wangjb@pku.edu.cn; 16; 7856-7864; 80
语种	中文
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/417111]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Xia, Ying,Ge, Rui,Chen, Li,et al. Palladium-Catalyzed Oxidative Cross-Coupling of Conjugated Enynones with Organoboronic Acids[J]. JOURNAL OF ORGANIC CHEMISTRY,2015.
APA	Xia, Ying.,Ge, Rui.,Chen, Li.,Liu, Zhen.,Xiao, Qing.,...&Wang, Jianbo.(2015).Palladium-Catalyzed Oxidative Cross-Coupling of Conjugated Enynones with Organoboronic Acids.JOURNAL OF ORGANIC CHEMISTRY.
MLA	Xia, Ying,et al."Palladium-Catalyzed Oxidative Cross-Coupling of Conjugated Enynones with Organoboronic Acids".JOURNAL OF ORGANIC CHEMISTRY (2015).