Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria

CORC > 青岛生物能源与过程研究所 > 中国科学院青岛生物能源与过程研究所 > 微生物代谢工程团队

	Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria
	Tan, Xiaoming; Yao, Lun; Gao, Qianqian; Wang, Weihua; Qi, Fengxia; Lu, Xuefeng
刊名	METABOLIC ENGINEERING
	2011-03-01
卷号	13 期号:2 页码:169-176
关键词	Fatty alcohol Hydrocarbon Biofuel Cyanobacterium
中文摘要	The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its conversion to high quality biofuel products are obstacles that must be overcome. Here we describe the biosynthesis of fatty alcohols in a genetically engineered cyanobacterial system through heterologously expressing fatty acyl-CoA reductase and the effect of environmental stresses on the production of fatty alcohols in the mutant strains. Hydrocarbon production in three representative types of native cyanobacterial model strains and the mutant strain overexpressing acetyl-CoA carboxylase was evaluated. The results of this investigation demonstrate the potential for direct production of high value chemicals and high energy fuels in a single biological system that utilizes solar energy as the energy source and carbon dioxide as the carbon source. (C) 2011 Elsevier Inc. All rights reserved.
英文摘要	The production of high value biochemicals and high energy biofuels from sustainable resources through the use of microbial based, green conversion technologies could reduce the dependence on petrochemical resources. However, a sustainable source of carbon and a clean, cost effective method for its conversion to high quality biofuel products are obstacles that must be overcome. Here we describe the biosynthesis of fatty alcohols in a genetically engineered cyanobacterial system through heterologously expressing fatty acyl-CoA reductase and the effect of environmental stresses on the production of fatty alcohols in the mutant strains. Hydrocarbon production in three representative types of native cyanobacterial model strains and the mutant strain overexpressing acetyl-CoA carboxylase was evaluated. The results of this investigation demonstrate the potential for direct production of high value chemicals and high energy fuels in a single biological system that utilizes solar energy as the energy source and carbon dioxide as the carbon source. (C) 2011 Elsevier Inc. All rights reserved.
学科主题	生物代谢工程
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Biotechnology & Applied Microbiology
研究领域[WOS]	Biotechnology & Applied Microbiology
关键词[WOS]	BLUE-GREEN ALGAE ; BIOFUELS PRODUCTION ; CELLULOSIC ETHANOL ; BIOSYNTHESIS ; BIOMASS ; OVERPRODUCTION ; CHALLENGES ; ALKANES ; ENZYME ; FUELS
收录类别	SCI
语种	英语
WOS记录号	WOS:000287963200005
公开日期	2011-09-09
内容类型	期刊论文
源URL	[http://ir.qibebt.ac.cn//handle/337004/658]
专题	青岛生物能源与过程研究所_微生物代谢工程团队
作者单位	Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, Key Lab Biofuels, Qingdao 266101, Peoples R China
推荐引用方式 GB/T 7714	Tan, Xiaoming,Yao, Lun,Gao, Qianqian,et al. Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria[J]. METABOLIC ENGINEERING,2011,13(2):169-176.
APA	Tan, Xiaoming,Yao, Lun,Gao, Qianqian,Wang, Weihua,Qi, Fengxia,&Lu, Xuefeng.(2011).Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria.METABOLIC ENGINEERING,13(2),169-176.
MLA	Tan, Xiaoming,et al."Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria".METABOLIC ENGINEERING 13.2(2011):169-176.