Asymmetric synthesis of N-protected chiral 1-aminoalkylphosphonic acids and synthesis of side chain-functionalized depsiphosphonopeptides | |
Liu, H ; Cai, SZ ; Xu, JX | |
刊名 | journal of peptide science |
2006 | |
关键词 | aminoalkylphosphonic acid asymmetric synthesis chlorophosphite depsiphosphonopeptide peptide phosphonopeptide HYDROGEN ALPHA-(BENZYLOXYCARBONYLAMINO)BENZYLPHOSPHONATES PHOSPHONATE DIESTERS CONVENIENT SYNTHESIS FACILE SYNTHESIS P-31 NMR ACTIVATION ALCOHOLS ESTERS |
DOI | 10.1002/psc.731 |
英文摘要 | Optically active 1-aminoalkylphosphonic acid derivatives were synthesized in moderate yields and optical purities via Mannich-type reactions of benzyl carbamate. aldehydes, and optically pure chlorophosphites. Side chain-functionalized depsiphosphonopeptides were also prepared in satisfactory yields directly from one-pot reactions of benzyl carbamate, aldehydes, and diethyl (R,R)-2-chloro-1,3,2-dioxaphospholane-4,5-dicarboxylate. Copyright (c) 2005 European Peptide Society and John Wiley & Sons, Ltd.; Biochemistry & Molecular Biology; Chemistry, Analytical; SCI(E); PubMed; 0; ARTICLE; 5; 337-340; 12 |
语种 | 英语 |
内容类型 | 期刊论文 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/345910] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Liu, H,Cai, SZ,Xu, JX. Asymmetric synthesis of N-protected chiral 1-aminoalkylphosphonic acids and synthesis of side chain-functionalized depsiphosphonopeptides[J]. journal of peptide science,2006. |
APA | Liu, H,Cai, SZ,&Xu, JX.(2006).Asymmetric synthesis of N-protected chiral 1-aminoalkylphosphonic acids and synthesis of side chain-functionalized depsiphosphonopeptides.journal of peptide science. |
MLA | Liu, H,et al."Asymmetric synthesis of N-protected chiral 1-aminoalkylphosphonic acids and synthesis of side chain-functionalized depsiphosphonopeptides".journal of peptide science (2006). |
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