In vivo and in situ detection of colorectal cancer using Fourier   transform infrared spectroscopy

CORC > 北京大学 > 化学与分子工程学院

	In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy
	Li, Qing-Bo ; Xu, Zhi ; Zhang, Neng-Wei ; Zhang, Li ; Wang, Fan ; Yang, Li-Min ; Wang, Jian-Sheng ; Zhou, Su ; Zhang, Yuan-Fu ; Zhou, Xiao-Si ; Shi, Jing-Sen ; Wu, Jin-Guang
刊名	world journal of gastroenterology
	2005
关键词	Colorectal cancer Fourier transform infrared spectroscopy
英文摘要	AIM: Real-time and rapid identification of the malignant tissue can be performed during or before surgical operation. Here we aimed to detect in vivo and in situ colorectal cancer by using Fourier transform infrared (FTIR) spectroscopy and fiber-optic technology. METHODS: A total of five patients with large intestine cancer were detected in vivo and in situ. Of them, three cases of colon cancer and one case of cecum cancer were detected intraoperatively and in vivo by using a FTIR spectrometer during surgical operation, and one case of rectum cancer was explored non-invasively and in vivo before the surgical operation. Normal and malignant colorectal tissues were detected in vivo and in situ using FTIR spectroscopy on the basis of fundamental studies. RESULTS: There were significant differences between FTIR spectra of normal and malignant colorectal tissues detected in vivo and in situ. Experimental results revealed that the spectral characteristics of normal and malignant tissues found in vivo and in situ were similar to those obtained from in vitro measurement in our previous fundamental research. CONCLUSION: FTIR fiber-optic attenuated total reflectance (ATR) spectroscopy can identify in situ and in vivo colorectal cancer. FTIR spectroscopic method with fiber optics is a non-invasive, rapid, accurate and in vivo cancer detection technique in clinical diagnosis. (C) 2005 The WJG Press and Elsevier Inc. All rights reserved.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208224000005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Gastroenterology & Hepatology; SCI(E); 32; 3; 327-330; 11
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/313310]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Li, Qing-Bo,Xu, Zhi,Zhang, Neng-Wei,et al. In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy[J]. world journal of gastroenterology,2005.
APA	Li, Qing-Bo.,Xu, Zhi.,Zhang, Neng-Wei.,Zhang, Li.,Wang, Fan.,...&Wu, Jin-Guang.(2005).In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy.world journal of gastroenterology.
MLA	Li, Qing-Bo,et al."In vivo and in situ detection of colorectal cancer using Fourier transform infrared spectroscopy".world journal of gastroenterology (2005).