Fluorescence dynamics of interactions between polyamide PyPyPy beta Dp   and DNA

doi:10.1007/s11426-005-0025-6

CORC > 北京大学 > 化学与分子工程学院

	Fluorescence dynamics of interactions between polyamide PyPyPy beta Dp and DNA
	Zhang, HJ ; Wang, J ; Wu, YS ; Yuan, G ; Ai, XC ; Wang, L ; Zhang, JP
刊名	中国科学b辑化学英文版
	2006
关键词	polyamide (PPP) calf thymus DNA (ctDNA) time-resolved fluorescence spectroscopy recognition dynamics MINOR-GROOVE MOLECULAR RECOGNITION DISTAMYCIN-A SPECIFICITY NETROPSIN
DOI	10.1007/s11426-005-0025-6
英文摘要	The photophysical properties of the polyamide PyPyPy beta Dp (PPP) were investigated by means of steady-state absorption and fluorescence spectroscopies, as well as time-resolved fluorescence spectroscopy. It was found that the excited-state properties of PIPP are very sensitive to solvents. In TKMC buffer PPP exhibited weak fluorescence with a decay time constant of 16 ps, while with the decrease of the solvent polarity PPP showed the blue-shifted peak position, increased intensity and lengthened life-time for its fluorescence behavior. In the presence of calf thymus DNA, it was observed that the fluorescence intensity was enhanced and the fluorescence lifetime increased from 16 to 32 ps for PPP, which verified that PPP bound into the minor groove of DNA duplex.; Chemistry, Multidisciplinary; SCI(E); EI; 0; ARTICLE; 1; 75-80; 49
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/252358]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhang, HJ,Wang, J,Wu, YS,et al. Fluorescence dynamics of interactions between polyamide PyPyPy beta Dp and DNA[J]. 中国科学b辑化学英文版,2006.
APA	Zhang, HJ.,Wang, J.,Wu, YS.,Yuan, G.,Ai, XC.,...&Zhang, JP.(2006).Fluorescence dynamics of interactions between polyamide PyPyPy beta Dp and DNA.中国科学b辑化学英文版.
MLA	Zhang, HJ,et al."Fluorescence dynamics of interactions between polyamide PyPyPy beta Dp and DNA".中国科学b辑化学英文版 (2006).