Layered double hydroxide-hemin nanocomposite as mimetic peroxidase and   its application in sensing

doi:10.1016/j.snb.2013.10.097

CORC > 北京大学 > 化学与分子工程学院

	Layered double hydroxide-hemin nanocomposite as mimetic peroxidase and its application in sensing
	Zhang, Fang-Ting ; Long, Xia ; Zhang, De-Wen ; Sun, Yi-Lun ; Zhou, Ying-Lin ; Ma, Yu-Rong ; Qi, Li-Min ; Zhang, Xin-Xiang
刊名	sensors and actuators b chemical
	2014
关键词	Fe-Ni layered double hydroxide Hemin Mimetic peroxidase Electrochemical sensor HYDROGEN-PEROXIDE HORSERADISH-PEROXIDASE ENZYME NANOPARTICLES ELECTRODE H2O2 REDUCTION MECHANISM
DOI	10.1016/j.snb.2013.10.097
英文摘要	A novel mimetic peroxidase, layered double hydroxide (LDH)-hemin nanocomposite, was first prepared by immobilizing hemin between the nanosheets of Fe-Ni LDH obtained through hydrothermal method. It showed an improved peroxidase-like activity to H2O2 compared with hemin alone, which was proved by UV-Vis spectroscopy and electrochemical measurements. The electrochemical sensor based on Fe-Ni LDH-hemin nanocomposite exhibited a fast response to H2O2 with good linear range of 1-240 mu M, a detection limit of 0.3 mu M based on a signal-to-noise ratio of 3 and high selectivity. It performed better than the sensors based on HRP and hemin which were prepared in the same conditions. The high performance of the sensor made LDH-hemin nanocomposite a promising mimetic peroxidase to replace natural enzymes. (C) 2013 Elsevier B.V. All rights reserved.; Chemistry, Analytical; Electrochemistry; Instruments & Instrumentation; SCI(E); 7; ARTICLE; zhouyl@pku.edu.cn; yurong.ma@pku.edu.cn; zxx@pku.edu.cn; 150-156; 192
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/215536]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Zhang, Fang-Ting,Long, Xia,Zhang, De-Wen,et al. Layered double hydroxide-hemin nanocomposite as mimetic peroxidase and its application in sensing[J]. sensors and actuators b chemical,2014.
APA	Zhang, Fang-Ting.,Long, Xia.,Zhang, De-Wen.,Sun, Yi-Lun.,Zhou, Ying-Lin.,...&Zhang, Xin-Xiang.(2014).Layered double hydroxide-hemin nanocomposite as mimetic peroxidase and its application in sensing.sensors and actuators b chemical.
MLA	Zhang, Fang-Ting,et al."Layered double hydroxide-hemin nanocomposite as mimetic peroxidase and its application in sensing".sensors and actuators b chemical (2014).