Cu(I)-catalyzed reaction of diazo compounds with terminal alkynes: a   direct synthesis of trisubstituted furans

doi:10.1016/j.tet.2014.07.086

CORC > 北京大学 > 化学与分子工程学院

	Cu(I)-catalyzed reaction of diazo compounds with terminal alkynes: a direct synthesis of trisubstituted furans
	Hossain, Mohammad Lokman ; Ye, Fei ; Zhang, Yan ; Wang, Jianbo
刊名	tetrahedron
	2014
关键词	Diazo compounds Alkyne Furan synthesis Copper catalyst Pyrrole synthesis ALPHA-DIAZOCARBONYL COMPOUNDS POLYSUBSTITUTED FURANS REGIOSELECTIVE SYNTHESIS RHODIUM CARBENOIDS ORGANIC-SYNTHESIS CYCLIZATION KETONES STRAIGHTFORWARD CYCLOADDITION HETEROCYCLES
DOI	10.1016/j.tet.2014.07.086
英文摘要	A method for the synthesis of tri-substituted furans has been developed based on Cu(I)-catalyzed reaction of terminal alkynes with beta-keto alpha-diazoesters. This method for the synthesis of 2,3,5-trisubstituted furans is operationally simple and applicable to wide substrate scope. Moreover, this synthesis employs cheap Cu(MeCN)(4)PF6 as the catalyst and no additional ligand is needed. Similar reaction has also been applied to ethyl (E)-2-diazo-3-(methoxyimino)butanoate for the synthesis of 2,3,5-trisubstituted N-methoxypyrroles with limited success. (C) 2014 Elsevier Ltd. All rights reserved.; Chemistry, Organic; SCI(E); 1; ARTICLE; wangjb@pku.edu.cn; 39; 6957-6962; 70
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/208733]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Hossain, Mohammad Lokman,Ye, Fei,Zhang, Yan,et al. Cu(I)-catalyzed reaction of diazo compounds with terminal alkynes: a direct synthesis of trisubstituted furans[J]. tetrahedron,2014.
APA	Hossain, Mohammad Lokman,Ye, Fei,Zhang, Yan,&Wang, Jianbo.(2014).Cu(I)-catalyzed reaction of diazo compounds with terminal alkynes: a direct synthesis of trisubstituted furans.tetrahedron.
MLA	Hossain, Mohammad Lokman,et al."Cu(I)-catalyzed reaction of diazo compounds with terminal alkynes: a direct synthesis of trisubstituted furans".tetrahedron (2014).