AB(2)-Type Amphiphilic Block Copolymers Composed of Poly(ethylene   glycol) and Poly(N-isopropylacrylamide) via Single-Electron Transfer   Living Radical Polymerization: Synthesis and Characterization

doi:10.1002/pola.23495

CORC > 北京大学 > 化学与分子工程学院

	AB(2)-Type Amphiphilic Block Copolymers Composed of Poly(ethylene glycol) and Poly(N-isopropylacrylamide) via Single-Electron Transfer Living Radical Polymerization: Synthesis and Characterization
	Tang, Xinde ; Liang, Xiaochao ; Yang, Qian ; Fan, Xinghe ; Shen, Zhihao ; Zhou, Qifeng
刊名	journal of polymer science part a polymer chemistry
	2009
关键词	AB(2)-type amphiphiles amphiphilic block copolymer atom transfer radical polymerization (ATRP) block copolymers poly(ethylene glycol) poly(N-isopropylacrylamide) single-electron transfer living radical polymerization (SET-LRP) star polymers stimuli-sensitive polymers SET-LRP N-ISOPROPYLACRYLAMIDE METHYL ACRYLATE VINYL-CHLORIDE THERMAL-PROPERTIES AQUEOUS-SOLUTIONS DRUG-DELIVERY ABC MIKTOARM 25-DEGREES-C WATER
DOI	10.1002/pola.23495
英文摘要	Novel AB(2)-type amphiphilic block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide), PEG-b-(PNIPAM)(2), were successfully synthesized through single-electron transfer living radical polymerization (SET-LRP). A difunctional macroinitiator was prepared by esterification of 2,2-dichloroacetyl chloride with poly(ethylene glycol) monomethyl ether (PEG). The copolymers were obtained via the SET-LRP of N-isopropylacrylamide (NIPAM) with CuCl/tris(2-(dimethylamino)ethyl)amine (Me6TREN) as catalytic system and DMF/H2O (v/v = 3:1) mixture as solvent. The resulting copolymers were characterized by gel permeation chromatography and H-1 NMR. These block copolymers show controllable molecular weights and narrow molecular weight distributions (PDI < 1.15). Their phase transition temperatures and the corresponding enthalpy changes in aqueous solution were measured by differential scanning calorimetry. As a result, the phase transition temperature of PEG(44)-b-(PNIPAM(55))(2) is similar to that in the case of PEG(44)-b-PNIPAM(110); however, the corresponding enthalpy change is much lower, indicating the significant influence of the macromolecular architecture on the phase transition. This is the first study into the effect of macromolecular architecture on the phase transition using AB(2)-type amphiphilic block copolymer composed of PEG and PNIPAM. (C) 2009 Wiley Periodicals, Inc. J Polyrn Sci Part A: Polym Chem 47: 4420-4427, 2009; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000269090300018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Polymer Science; SCI(E); EI; 65; ARTICLE; 17; 4420-4427; 47
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/151413]
专题	化学与分子工程学院
推荐引用方式 GB/T 7714	Tang, Xinde,Liang, Xiaochao,Yang, Qian,et al. AB(2)-Type Amphiphilic Block Copolymers Composed of Poly(ethylene glycol) and Poly(N-isopropylacrylamide) via Single-Electron Transfer Living Radical Polymerization: Synthesis and Characterization[J]. journal of polymer science part a polymer chemistry,2009.
APA	Tang, Xinde,Liang, Xiaochao,Yang, Qian,Fan, Xinghe,Shen, Zhihao,&Zhou, Qifeng.(2009).AB(2)-Type Amphiphilic Block Copolymers Composed of Poly(ethylene glycol) and Poly(N-isopropylacrylamide) via Single-Electron Transfer Living Radical Polymerization: Synthesis and Characterization.journal of polymer science part a polymer chemistry.
MLA	Tang, Xinde,et al."AB(2)-Type Amphiphilic Block Copolymers Composed of Poly(ethylene glycol) and Poly(N-isopropylacrylamide) via Single-Electron Transfer Living Radical Polymerization: Synthesis and Characterization".journal of polymer science part a polymer chemistry (2009).