Nanoparticle: is it promising in capillary electrophoresis? | |
Zhang, Zhengxiang ; Yan, Bo ; Liao, Yiping ; Liu, Huwei | |
2008 | |
关键词 | ALKYLTHIOL GOLD NANOPARTICLES ELECTROCHROMATOGRAPHY SEPARATION DNA PHASES |
英文摘要 | The nanoparticles, due to their large surface-to-volume ratio and favorable surface chemistry, are improving the separation in capillary and chip-based electrophoresis with higher efficiency, selectivity, and better reproducibility. The citrate-stabilized gold nanoparticles were taken to demonstrate the applications of nanoparticles in capillary electrophoresis. An important application of the gold nanoparticles discussed is a pseudo-stationary phase in the presence of poly(ethylene oxide) (PEO) for double-standard DNA separation. The challenges that are still required to meet the basic requirement for the nanoparticles for use in CE, include acceptable stability in a variety of electrolytes, discriminating interactions with the analytes, and equal mobility to prevent band broadening.; http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255996900028&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701 ; Biochemical Research Methods; Chemistry, Analytical; SCI(E); EI; CPCI-S(ISTP); PubMed; 28 |
语种 | 英语 |
DOI标识 | 10.1007/s00216-008-1930-2 |
内容类型 | 其他 |
源URL | [http://ir.pku.edu.cn/handle/20.500.11897/150242] |
专题 | 化学与分子工程学院 |
推荐引用方式 GB/T 7714 | Zhang, Zhengxiang,Yan, Bo,Liao, Yiping,et al. Nanoparticle: is it promising in capillary electrophoresis?. 2008-01-01. |
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