Understanding molecular mechanisms of traditional Chinese medicine for   the treatment of influenza viruses infection by computational approaches

doi:10.1039/c3mb70268e

CORC > 北京大学 > 化学与分子工程学院

	Understanding molecular mechanisms of traditional Chinese medicine for the treatment of influenza viruses infection by computational approaches
	Gu, Shuo ; Yin, Ning ; Pei, Jianfeng ; Lai, Luhua
刊名	分子生物系统
	2013
关键词	A VIRUS NEURAMINIDASE HEMAGGLUTININ INHIBITORS BINDING FLAVONOIDS RECEPTOR DOCKING COMPLEX DESIGN
DOI	10.1039/c3mb70268e
英文摘要	The battle against influenza is an enduring one. For hundreds of years, people have fought such small viruses with practices such as traditional Chinese medicine (TCM), however only recently has it been possible to use cutting-edge technology to investigate their mechanisms. Here, we re-created this ancient Chinese knowledge to explore the chemistry of herbs and elucidate their mechanism of action using molecular computational methods. Our results show that TCM compounds can inhibit influenza viral proteins in a multi-target/multi-component manner, revealing the versatility of TCM for treating different influenza virus subtypes, including the recently emerged H7N9.; Biochemistry & Molecular Biology; SCI(E); PubMed; 2; ARTICLE; 11; 2696-2700; 9
语种	英语
内容类型	期刊论文
源URL	[http://ir.pku.edu.cn/handle/20.500.11897/149747]
专题	化学与分子工程学院生命科学学院
推荐引用方式 GB/T 7714	Gu, Shuo,Yin, Ning,Pei, Jianfeng,et al. Understanding molecular mechanisms of traditional Chinese medicine for the treatment of influenza viruses infection by computational approaches[J]. 分子生物系统,2013.
APA	Gu, Shuo,Yin, Ning,Pei, Jianfeng,&Lai, Luhua.(2013).Understanding molecular mechanisms of traditional Chinese medicine for the treatment of influenza viruses infection by computational approaches.分子生物系统.
MLA	Gu, Shuo,et al."Understanding molecular mechanisms of traditional Chinese medicine for the treatment of influenza viruses infection by computational approaches".分子生物系统 (2013).