Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth

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	Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth
	Wang, R; Zhu, PF; Yang, WY; Gao, S; Li, B; Li, Q; Li, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
刊名	MATERIALS & DESIGN
	2018-04-15
卷号	144 页码:304-309
关键词	Embryonic Stem-cells Bone Scaffolds Hydrogel Scaffolds Culture-systems Silk Fibroin Titanium 2d Regeneration Osteogenesis
ISSN号	0264-1275
英文摘要	In this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.; In this work, three-dimensional (3D) periodic TiO2 bio-ceramic scaffolds were created by continuous filament writing with TiO2 sol-gel ink followed by sintering. The TiO2 sol-gel ink has the advantage of creating 3D bio-ceramic scaffolds with finer feature size than commonly used ceramic powder based ink systems. The structure, pore sizes, and interconnectivity could be controlled through 3D structure design and printing parameter adjustment. To evaluate the potential of these 3D TiO2 bio-ceramic scaffolds for bone tissue engineering, the mouse osteoblastic cell line MC3T3-E1 was cultured on them. The observed good viability demonstrated that 3D TiO2 bio-ceramic scaffolds created by direct-writing technique provide a biocompatible environment that favors cell growth and attachment. (C) 2018 Elsevier Ltd. All rights reserved.
学科主题	Materials Science, Multidisciplinary
语种	英语
资助机构	Shenyang National Laboratory for Materials Science [Y4N56R1161, Y4N56F2161]; National Natural Science Foundation of China [51672283, 51602316]; Science and Technology Plan of Shenzhen City [JCYJ20150827165038323, JCYJ20160301154309393]
公开日期	2018-06-05
内容类型	期刊论文
源URL	[http://ir.imr.ac.cn/handle/321006/79360]
专题	金属研究所_中国科学院金属研究所
通讯作者	Li, Q (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang Natl Lab Mat Sci, Environm Funct Mat Div, Shenyang 110016, Liaoning, Peoples R China.
推荐引用方式 GB/T 7714	Wang, R,Zhu, PF,Yang, WY,et al. Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth[J]. MATERIALS & DESIGN,2018,144:304-309.
APA	Wang, R.,Zhu, PF.,Yang, WY.,Gao, S.,Li, B.,...&Li, Q .(2018).Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth.MATERIALS & DESIGN,144,304-309.
MLA	Wang, R,et al."Direct-writing of 3D periodic TiO2 bio-ceramic scaffolds with a sol-gel ink for in vitro cell growth".MATERIALS & DESIGN 144(2018):304-309.