A new lignan from the Jian-er syrup and its content determination by RP-HPLC

CORC > 南海海洋研究所 > 中国科学院南海海洋研究所 > 广东省海洋药物重点实验室

	A new lignan from the Jian-er syrup and its content determination by RP-HPLC
	Wu, J; Yang, MH; Guo, Y; Jin, Y; Xu, XD; yangmeihua15@hotmail.com; Chen, JM
刊名	JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
	2006
卷号	41 期号:2 页码:662-666
关键词	Lignan 6 '-hydroxy-justicidin b Structural Elucidation Content Determination High Performance Liquid Chromatography The Jian-er Syrup
ISSN号	0731-7085
英文摘要	The Jian-er syrup is a commonly used traditional Chinese medicinal preparation refined from two herbs, Metaplexis japonica (Thunb.) Makino and Justicia procumbens L. A new lignan, named 6'-hydroxy-Justicidin B, was isolated from the ethyl acetate extract of the Jian-er syrup and its structure was established on the basis of spectral analysis. The content of 6'-hydroxy-Justicidin B in the Jian-er syrup was determined by RP-HPLC for the first time. Chromatographic separation was achieved on an Agilent Zorbax SB-C-18 column (150 mm x 4.6 mm i.d., 5 mu m) at 25 degrees C and the mobile phase was a mixture of acetonitrile and water (31:69 v/v) detected at 256 nm at a flow rate of 1.0 ml/min. This method was validated in terms of selectivity, linearity, precision, accuracy, limit of detection, limit of quantitation and solution stability. It can be used to control the quality of this preparation effectively. (c) 2005 Elsevier B.V. All rights reserved.
学科主题	Chemistry, Analytical ; Pharmacology & Pharmacy
URL标识	查看原文
资助项目	广东省海洋药物重点实验室
WOS记录号	WOS:000237705700049
公开日期	2011-07-03
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/5200]
专题	南海海洋研究所_广东省海洋药物重点实验室
通讯作者	yangmeihua15@hotmail.com
推荐引用方式 GB/T 7714	Wu, J,Yang, MH,Guo, Y,et al. A new lignan from the Jian-er syrup and its content determination by RP-HPLC[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2006,41(2):662-666.
APA	Wu, J.,Yang, MH.,Guo, Y.,Jin, Y.,Xu, XD.,...&Chen, JM.(2006).A new lignan from the Jian-er syrup and its content determination by RP-HPLC.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,41(2),662-666.
MLA	Wu, J,et al."A new lignan from the Jian-er syrup and its content determination by RP-HPLC".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 41.2(2006):662-666.