Antifungal Cyclic Peptides from Psammosilene tunicoides

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	Antifungal Cyclic Peptides from Psammosilene tunicoides
	wdzhangy@hotmail.com; Tian, JM; Shen, YH; Yang, XW; Liang, SA; Shan, L; Li, HL; Liu, RH; Zhang, WD; shenyunheng9217018@yahoo.com.cn
刊名	JOURNAL OF NATURAL PRODUCTS
	2010
卷号	73 期号:12 页码:1987-1992
ISSN号	0163-3864
英文摘要	Three new cyclic peptides, tunicyclins B-D, and a known cyclic peptide, psammosilenin B, were isolated from the root of Psammosilene tunicoides. The structures of new cyclic peptides were elucidated by extensive NMR and MS analysis. Tunicyclin B contains an unusual alpha,beta-dehydrotryptophan (Delta(Z)-Trp) residue, previously reported from marine sponges and bacteria. Tunicyclin D showed a broad spectrum of antifungal activity against Candida albicans (SC5314), Candida albicans (Y0109), Candida tropicalis, Candida parapsilosis, and Cryptococcus neoformans (BLS 108) with MIC80 values of 4.0, 16.0, 0.25, 1.0, and 1.0 mu g mL(-1), respectively.
学科主题	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
URL标识	查看原文
资助项目	LMB
WOS记录号	WOS:000285560000003
公开日期	2011-07-02
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/3712]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
通讯作者	wdzhangy@hotmail.com; shenyunheng9217018@yahoo.com.cn
推荐引用方式 GB/T 7714	wdzhangy@hotmail.com,Tian, JM,Shen, YH,et al. Antifungal Cyclic Peptides from Psammosilene tunicoides[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(12):1987-1992.
APA	wdzhangy@hotmail.com.,Tian, JM.,Shen, YH.,Yang, XW.,Liang, SA.,...&shenyunheng9217018@yahoo.com.cn.(2010).Antifungal Cyclic Peptides from Psammosilene tunicoides.JOURNAL OF NATURAL PRODUCTS,73(12),1987-1992.
MLA	wdzhangy@hotmail.com,et al."Antifungal Cyclic Peptides from Psammosilene tunicoides".JOURNAL OF NATURAL PRODUCTS 73.12(2010):1987-1992.