New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity

CORC > 南海海洋研究所 > 中国科学院南海海洋研究所 > 中科院海洋生物资源可持续利用重点实验室

	New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity
	Cheng, Zhi-Qiang ; Bao, Jie 1; He, Fei ; Yu, Jin-Hai ; Zhai, Huijuan ; Jiang, Cheng-Shi ; Zhang, Yuying ; Zhang, Yun 2; Zhang, Xiaoyong 3; Chen, Guangying 1
刊名	MOLECULES
	2018
卷号	23 期号:8 页码:1982
关键词	Arthrinium sp. chromone polyketide antioxidant activity
ISSN号	1420-3049
英文摘要	Five new chromone derivatives, arthones A-E (1-5), together with eight known biogenetically related cometabolites (6-13), were isolated from a deep-sea-derived fungus Arthrinium sp. UJNMF0008. Their structures were assigned by detailed analyses of spectroscopic data, while the absolute configurations of 1 and 5 were established by electronic circular dichroism (ECD) calculations and that of 2 was determined by modified Mosher ester method. Compounds 3 and 8 exhibited potent antioxidant property with DPPH and ABTS radical scavenging activities, with IC50 values ranging from 16.9 to 18.7 mu M. Meanwhile, no compounds indicated obvious bioactivity in our antimicrobial and anti-inflammatory assays at 50.0 mu M.
内容类型	期刊论文
源URL	[http://ir.scsio.ac.cn/handle/344004/17648]
专题	南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位	1.Univ Jinan, Sch Biol Sci & Technol, 336 West Rd Nan Xinzhuang, Jinan 250022, Shandong, Peoples R China 2.Hainan Normal Univ, Minist Educ, Key Lab Trop Med Plant Chem, 99 South Rd Longkun Rd, Haikou 571158, Hainan, Peoples R China 3.Chinese Acad Sci, South China Sea Inst Oceanol, Key Lab Trop Marine Bioresources & Ecol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China 4.South China Agr Univ, Coll Marine Sci, 483 Wushan Rd, Guangzhou 510642, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Cheng, Zhi-Qiang,Bao, Jie,He, Fei,et al. New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity[J]. MOLECULES,2018,23(8):1982.
APA	Cheng, Zhi-Qiang.,Bao, Jie.,He, Fei.,Yu, Jin-Hai.,Zhai, Huijuan.,...&Zhang, Hua.(2018).New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity.MOLECULES,23(8),1982.
MLA	Cheng, Zhi-Qiang,et al."New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity".MOLECULES 23.8(2018):1982.