Variecolortins A-C, Three Pairs of Spirocyclic Diketopiperazine Enantiomers from the Marine-Derived Fungus Eurotium sp SCSIO F452 | |
Zhang, Weimin3; Zhang, Si; Long, Lijuan; Wang, Fazuo; Zhong, Weimao1; Wang, Junfeng; Wei, Xiaoyi2; Fu, Tingdan4; Chen, Yuchan3; Xiang, Yao | |
刊名 | ORGANIC LETTERS
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2018 | |
卷号 | 20期号:15页码:4593 |
ISSN号 | 1523-7060 |
英文摘要 | Three pairs of spirocyclic diketopiperazine enantiomers, variecolortins A-C (1-3), were isolated from marine-derived fungus Eurotium sp. SCSIO F452. Compound 1 possesses an unprecedented highly functionalized seco-anthronopyranoid carbon skeleton featuring a 2-oxa-7-azabicyclo[3.2.1]octane core. Compounds 2 and 3 represent rare examples of a 6/6/6/6 tetracyclic cyclohexene anthrone carbon scaffold. Their structures were determined by spectroscopic analyses, X-ray diffraction, and ECD calculations. Their enantiomers exhibited different antioxidative and cytotoxic activities, and their modes of action were investigated. |
内容类型 | 期刊论文 |
源URL | [http://ir.scsio.ac.cn/handle/344004/17647] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
作者单位 | 1.Guangzhou Univ Chinese Med, Inst Trop Med, Guangzhou 510400, Guangdong, Peoples R China 2.Chinese Acad Sci, South China Sea Inst Oceanol, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med,RNAM Ctr Marine, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China 3.Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou 510650, Guangdong, Peoples R China 4.Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangdong Prov Key Lab Microbial Culture Collect, Guangdong Open Lab Appl Microbiol, 100 Cent Xianlie Rd, Guangzhou 510070, Guangdong, Peoples R China 5.Univ Chinese Acad Sci, 19 Yuquan Rd, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Weimin,Zhang, Si,Long, Lijuan,et al. Variecolortins A-C, Three Pairs of Spirocyclic Diketopiperazine Enantiomers from the Marine-Derived Fungus Eurotium sp SCSIO F452[J]. ORGANIC LETTERS,2018,20(15):4593, 4596. |
APA | Zhang, Weimin.,Zhang, Si.,Long, Lijuan.,Wang, Fazuo.,Zhong, Weimao.,...&Xiao, Zhihui.(2018).Variecolortins A-C, Three Pairs of Spirocyclic Diketopiperazine Enantiomers from the Marine-Derived Fungus Eurotium sp SCSIO F452.ORGANIC LETTERS,20(15),4593. |
MLA | Zhang, Weimin,et al."Variecolortins A-C, Three Pairs of Spirocyclic Diketopiperazine Enantiomers from the Marine-Derived Fungus Eurotium sp SCSIO F452".ORGANIC LETTERS 20.15(2018):4593. |
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