Exosomes as drug carriers for clinical application | |
Di, Cuixia1,2; Zhang, Qianjing1,2,3; Wang, Yupei1,2,3; Wang, Fang1,2,3; Chen, Yuhong1,2,3; Gan, Lu1,2,3; Zhou, Rong1,2; Sun, Chao1,2; Li, Hongyan1,2; Zhang, Xuetian1,2,3 | |
刊名 | ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY |
2018 | |
卷号 | 46页码:S564-S570 |
关键词 | Exosomes nanoparticle tumor drug carrier chemotherapy radiotherapy |
ISSN号 | 2169-1401 |
DOI | 10.1080/21691401.2018.1501381 |
通讯作者 | Zhang, Hong(zhang.h@impcas.ac.cn) |
英文摘要 | Exosomes are nanoscale vesicles shed from all cell types and play a major role in communication and transportation of materials between cells due to their ability to transfer proteins and nucleic acids from one cell to another. Analogous in size and function to synthetic nanoparticles, exosomes offer many advantages, rendering them the most promising candidates for targeted drug or gene delivery vehicles. Exosomes can also induce chemoresistance or radioresistance of tumor cells. Studies about the related mechanisms help overcome cancer therapy resistance to some extent. In this review, we focus on the application of exosomes as nanocarriers and the current status of the application of exosomes to cancer therapy. |
收录类别 | SCI |
WOS关键词 | EXTRACELLULAR VESICLES ; DELIVERY VEHICLES ; STROMAL CELLS ; CANCER ; RESISTANCE ; BRAIN ; RNA ; NANOCARRIERS ; PERSPECTIVES ; FIBROBLASTS |
WOS研究方向 | Biotechnology & Applied Microbiology ; Engineering ; Materials Science |
WOS类目 | Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials |
语种 | 英语 |
出版者 | TAYLOR & FRANCIS LTD |
WOS记录号 | WOS:000460141900054 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2555545 |
专题 | 寒区旱区环境与工程研究所 |
通讯作者 | Zhang, Hong |
作者单位 | 1.Chinese Acad Sci, Inst Modern Phys, Dept Radiat Med, Lanzhou, Gansu, Peoples R China 2.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou, Gansu, Peoples R China 3.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China 4.Med Coll Soochow, Sch Radiat Med & Protect, Suzhou, Peoples R China |
推荐引用方式 GB/T 7714 | Di, Cuixia,Zhang, Qianjing,Wang, Yupei,et al. Exosomes as drug carriers for clinical application[J]. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY,2018,46:S564-S570. |
APA | Di, Cuixia.,Zhang, Qianjing.,Wang, Yupei.,Wang, Fang.,Chen, Yuhong.,...&Zhang, Hong.(2018).Exosomes as drug carriers for clinical application.ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY,46,S564-S570. |
MLA | Di, Cuixia,et al."Exosomes as drug carriers for clinical application".ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY 46(2018):S564-S570. |
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