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Exosomes as drug carriers for clinical application
Di, Cuixia1,2; Zhang, Qianjing1,2,3; Wang, Yupei1,2,3; Wang, Fang1,2,3; Chen, Yuhong1,2,3; Gan, Lu1,2,3; Zhou, Rong1,2; Sun, Chao1,2; Li, Hongyan1,2; Zhang, Xuetian1,2,3
刊名ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY
2018
卷号46页码:S564-S570
关键词Exosomes nanoparticle tumor drug carrier chemotherapy radiotherapy
ISSN号2169-1401
DOI10.1080/21691401.2018.1501381
通讯作者Zhang, Hong(zhang.h@impcas.ac.cn)
英文摘要Exosomes are nanoscale vesicles shed from all cell types and play a major role in communication and transportation of materials between cells due to their ability to transfer proteins and nucleic acids from one cell to another. Analogous in size and function to synthetic nanoparticles, exosomes offer many advantages, rendering them the most promising candidates for targeted drug or gene delivery vehicles. Exosomes can also induce chemoresistance or radioresistance of tumor cells. Studies about the related mechanisms help overcome cancer therapy resistance to some extent. In this review, we focus on the application of exosomes as nanocarriers and the current status of the application of exosomes to cancer therapy.
收录类别SCI
WOS关键词EXTRACELLULAR VESICLES ; DELIVERY VEHICLES ; STROMAL CELLS ; CANCER ; RESISTANCE ; BRAIN ; RNA ; NANOCARRIERS ; PERSPECTIVES ; FIBROBLASTS
WOS研究方向Biotechnology & Applied Microbiology ; Engineering ; Materials Science
WOS类目Biotechnology & Applied Microbiology ; Engineering, Biomedical ; Materials Science, Biomaterials
语种英语
出版者TAYLOR & FRANCIS LTD
WOS记录号WOS:000460141900054
内容类型期刊论文
URI标识http://www.corc.org.cn/handle/1471x/2555545
专题寒区旱区环境与工程研究所
通讯作者Zhang, Hong
作者单位1.Chinese Acad Sci, Inst Modern Phys, Dept Radiat Med, Lanzhou, Gansu, Peoples R China
2.Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou, Gansu, Peoples R China
3.Univ Chinese Acad Sci, Coll Life Sci, Beijing, Peoples R China
4.Med Coll Soochow, Sch Radiat Med & Protect, Suzhou, Peoples R China
推荐引用方式
GB/T 7714
Di, Cuixia,Zhang, Qianjing,Wang, Yupei,et al. Exosomes as drug carriers for clinical application[J]. ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY,2018,46:S564-S570.
APA Di, Cuixia.,Zhang, Qianjing.,Wang, Yupei.,Wang, Fang.,Chen, Yuhong.,...&Zhang, Hong.(2018).Exosomes as drug carriers for clinical application.ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY,46,S564-S570.
MLA Di, Cuixia,et al."Exosomes as drug carriers for clinical application".ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY 46(2018):S564-S570.
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