Polydopamine-assisted Sr immobilization to improve the osteogenesis of a three-dimensional reduced graphene oxide/polypyrrole composite scaffold | |
Wang, Rui1,4; Song, Fuxiang1,2; Li, Sirui1; Ding, Lili1; Xu, Zexian1; Zhang, Biying1; Wang, Jingqing4; Li, Miao1; Liu, Bin1,2; Qiu, Yinong3 | |
刊名 | MATERIALS LETTERS |
2019-07-01 | |
卷号 | 246页码:182-185 |
关键词 | Strontium Graphene scaffold Biomaterials Porous materials Bone tissue engineering |
ISSN号 | 0167-577X |
DOI | 10.1016/j.matlet.2019.03.065 |
通讯作者 | Liu, Bin(liubkq@lzu.edu.cn) ; Qiu, Yinong(582569924@qq.com) |
英文摘要 | The development of a bone tissue engineering scaffold with a biologically active surface for fast bone cell adhesion, proliferation, and extracellular matrix mineralization has been hotly pursued in recent years. However, most substrate materials do not show enough biological activity. Here, polydopamine-assisted immobilization of strontium (Sr) endows a three-dimensional reduced graphene oxide/polypyrrole (3D rGO/PPY) composite scaffold with higher bioactivity. Compared to the bare 3D rGO/PPY scaffold, 3D rGO/PPY modified with Sr (3D rGO/PPY/PDA/Sr) has a higher surface roughness. Moreover, benefiting from the introduction of Sr, the 3D rGO/PPY/PDA/Sr scaffold can significantly enhance early adhesion and proliferation of MC3T3-E1 cells on the 2nd day of culture. Additionally, ALP activity and extracellular matrix mineralization are distinctly enhanced. (C) 2019 Elsevier B.V. All rights reserved. |
收录类别 | SCI |
WOS关键词 | FABRICATION ; TISSUES |
WOS研究方向 | Materials Science ; Physics |
WOS类目 | Materials Science, Multidisciplinary ; Physics, Applied |
语种 | 英语 |
出版者 | ELSEVIER SCIENCE BV |
WOS记录号 | WOS:000462761700047 |
内容类型 | 期刊论文 |
URI标识 | http://www.corc.org.cn/handle/1471x/2555517 |
专题 | 寒区旱区环境与工程研究所 |
通讯作者 | Liu, Bin; Qiu, Yinong |
作者单位 | 1.Lanzhou Univ, Sch Hosp Stomatol, Lanzhou, Gansu, Peoples R China 2.Lanzhou Univ, Sch Nucl Sci & Technol, Lanzhou, Gansu, Peoples R China 3.940th Hosp Joint Logist Support Force Chinese Peo, Dept Stomatol, Lanzhou, Gansu, Peoples R China 4.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Solid Lubricat, Lanzhou, Gansu, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Rui,Song, Fuxiang,Li, Sirui,et al. Polydopamine-assisted Sr immobilization to improve the osteogenesis of a three-dimensional reduced graphene oxide/polypyrrole composite scaffold[J]. MATERIALS LETTERS,2019,246:182-185. |
APA | Wang, Rui.,Song, Fuxiang.,Li, Sirui.,Ding, Lili.,Xu, Zexian.,...&Qiu, Yinong.(2019).Polydopamine-assisted Sr immobilization to improve the osteogenesis of a three-dimensional reduced graphene oxide/polypyrrole composite scaffold.MATERIALS LETTERS,246,182-185. |
MLA | Wang, Rui,et al."Polydopamine-assisted Sr immobilization to improve the osteogenesis of a three-dimensional reduced graphene oxide/polypyrrole composite scaffold".MATERIALS LETTERS 246(2019):182-185. |
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