Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups | |
Liu, Weixiang1,2,3,4; Qin, Yukun1,2,3; Liu, Song1,2,3; Xing, Ronge1,2,3; Yu, Huahua1,2,3; Chen, Xiaolin1,2,3; Li, Kecheng1,2,3; Li, Pengcheng1,2,3 | |
刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES |
2018-07-15 | |
卷号 | 114页码:942-949 |
关键词 | Quaternized chitosan Aminopyridine Antifungal |
ISSN号 | 0141-8130 |
DOI | 10.1016/j.ijbiomac.2018.03.179 |
通讯作者 | Qin, Yukun(ykqin@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn) |
英文摘要 | A novel type of water soluble chitosan derivatives (TQCSPX) were synthesized including 3-aminopyridine (TQCSPI) and 3-Amino-4-methylpyridine (TQCSP2). The theoretical structures of TQCSPX were calculated by Gaussian 09 and confirmed by FT-IR, H-1 NMR, C-13 NMR, elemental analysis and XRD. The antifungal properties of TQCSPX against Phytophthora capsici (P. capsici), Rhizoctonia solani (R. solani), Fusarium oxysporum (F. oxysporum) and Fusarium solani (F. solani) were evaluated at concentrations ranging from 0.2 mg/mL to 0.8 mg/mL Antifungal results indicated that the derivatives have significantly enhanced antifungal activity after quaternized compared with the original chitosan (CS). Moreover, TQCSPI inhibited the growth of P. capsici with inhibitory indices of 91.94% at 0.8 mg/mL The experimental results demonstrated that the increasing number of the positive charge would improve the antifungal efficiency of chitosan, which may provide a novel direction for the development of fungicides. (C) 2018 Elsevier B.V. All rights reserved. |
资助项目 | National Natural Science Foundation of China[41306071] ; Scientific and Technological Innovation Project - Qingdao National Laboratory for Marine Science and Technology[2015ASKJ02] ; Science and Technology Program - Qingdao[17-3-3-60-nsh] |
WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
语种 | 英语 |
出版者 | ELSEVIER SCIENCE BV |
WOS记录号 | WOS:000435056900108 |
内容类型 | 期刊论文 |
源URL | [http://ir.qdio.ac.cn/handle/337002/159406] |
专题 | 海洋研究所_实验海洋生物学重点实验室 |
通讯作者 | Qin, Yukun; Li, Pengcheng |
作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Liu, Weixiang,Qin, Yukun,Liu, Song,et al. Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2018,114:942-949. |
APA | Liu, Weixiang.,Qin, Yukun.,Liu, Song.,Xing, Ronge.,Yu, Huahua.,...&Li, Pengcheng.(2018).Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,114,942-949. |
MLA | Liu, Weixiang,et al."Synthesis, characterization and antifungal efficacy of chitosan derivatives with triple quaternary ammonium groups".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 114(2018):942-949. |
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