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	Natural gypenosides: targeting cancer through different molecular pathways
	Ahmad, Bashir1,2; Khan, Suliman1,3,4; Nabi, Ghulam4,5; Gamallat, Yaser2; Su, Pengyu2; Jamalat, Yazeed2; Duan, Pengfei1,3; Yao, Lunguang1,3
刊名	CANCER MANAGEMENT AND RESEARCH
	2019
卷号	11页码:2287-2297
关键词	cancer surgery chemotherapy radiation therapy Gyp oral lung leukemic colorectal hepatocellular
ISSN号	1179-1322
DOI	10.2147/CMAR.S185232
通讯作者	Nabi, Ghulam(ghulamnabiqau@gmail.com) ; Yao, Lunguang(lunguangyao@163.com)
英文摘要	The second foremost cause of mortality around the word is cancer. Conventional therapies, such as radiation, surgery, and chemotherapy have limited accessibility owing to secondary resistance. Therefore, convenient, safe, and nonresistant drugs are urgently needed. Plant-derived natural products have attracted considerable interest owing to their high efficacy, low toxicity, and convenience. Gypenosides (Gyp) inhibit invasion, migration, metastasis, and proliferation and induce apoptosis in different cancers, including oral, lung, colorectal, hepatocellular, and leukemic cancers through different molecular pathways. This review summarizes Gyp studies on cancer to serve as a reference for further research and clinical trials.
资助项目	National Science Foundation of China[31870917] ; Scientific and Technological Research Project of Henan Province[182102110084]
WOS关键词	NF-KAPPA-B ; ENDOPLASMIC-RETICULUM STRESS ; GYNOSTEMMA-PENTAPHYLLUM SAPONINS ; MITOCHONDRIA-DEPENDENT PATHWAYS ; INDUCED G0/G1 ARREST ; G2/M PHASE ARREST ; CELLS IN-VITRO ; MEDIATED APOPTOSIS ; SIGNALING PATHWAYS ; HERBAL MEDICINES
WOS研究方向	Oncology
语种	英语
出版者	DOVE MEDICAL PRESS LTD
WOS记录号	WOS:000463243300001
资助机构	National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; National Science Foundation of China ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province ; Scientific and Technological Research Project of Henan Province
内容类型	期刊论文
源URL	[http://ir.ihb.ac.cn/handle/342005/27869]
专题	水生生物研究所_其他
通讯作者	Nabi, Ghulam; Yao, Lunguang
作者单位	1.Nanyang Normal Univ, Henan Prov Engn Res Ctr Hlth Prod Livestock & Pou, Nanyang, Peoples R China 2.Dalian Med Univ, Coll Basic Med Sci, Dalian, Peoples R China 3.Nanyang Normal Univ, Sch Agr Engn, Collaborat Innovat Ctr Water Secur Water Source R, Divers Project Henan Prov,Key Lab Ecol Secur Wate, Nanyang, Peoples R China 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Chinese Acad Sci, Inst Hydrobiol, 7 South Rd East Lake, Wuhan 430072, Hubei, Peoples R China
推荐引用方式 GB/T 7714	Ahmad, Bashir,Khan, Suliman,Nabi, Ghulam,et al. Natural gypenosides: targeting cancer through different molecular pathways[J]. CANCER MANAGEMENT AND RESEARCH,2019,11:2287-2297.
APA	Ahmad, Bashir.,Khan, Suliman.,Nabi, Ghulam.,Gamallat, Yaser.,Su, Pengyu.,...&Yao, Lunguang.(2019).Natural gypenosides: targeting cancer through different molecular pathways.CANCER MANAGEMENT AND RESEARCH,11,2287-2297.
MLA	Ahmad, Bashir,et al."Natural gypenosides: targeting cancer through different molecular pathways".CANCER MANAGEMENT AND RESEARCH 11(2019):2287-2297.

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