Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome

doi:10.1080/10284150310001640356

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	Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome
	Liu, ZD ; Wang, DX ; Xue, QM ; Chen, J ; Li, YJ ; Bai, XL ; Chang, LW
刊名	NUTRITIONAL NEUROSCIENCE
	2003-12-01
卷号	6 期号:6 页码:389-392
关键词	Chronic Fatigue Syndrome Erythrocyte Membrane Fatty Acid Gas Chromatography
ISSN号	1028-415X
DOI	10.1080/10284150310001640356
英文摘要	Chronic fatigue syndrome (CFS) is an illness characterized by persistent and relapsing fatigue, often accompanied by numerous symptoms involving various systems of whole body. The etiology of CFS remains unclear. Literature reported whether the concentrations of the essential fatty acids in red cell membranes of CFS patients were decreased is controversial. In our study, Forty-two patients who fulfilled the diagnostic criteria defined by Centers for Disease Control and Prevention (CDC). Thirty-seven age- and sex-matched controls were selected from healthy medical staffs and volunteers. After lipid analysis, we found that the levels of the arachidonic acid (ARA) and docosahexanoic acid (DHA) were decreased in patients suffered from CFS. However, the levels of the palmitic acid and oleic acid were increased. We speculated that there are two possible mechanisms-one of which is that oxidative stress has led to an excessive oxidation and resulting in the above fatty acids. Alternatively, insufficiency of ingestion of fatty acids might not be the major cause.
语种	英语
出版者	TAYLOR & FRANCIS LTD
WOS记录号	WOS:000188240900008
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/80901]
专题	中国科学院化学研究所
通讯作者	Liu, ZD
作者单位	1.Capital Univ Med Sci, Affiliated Hosp, Beijing Friendship Hosp, Dept Neurol, Beijing 100050, Peoples R China 2.Beijing Kuangwuju Hosp, Dept Neurol, Beijing, Peoples R China 3.Acad Sinica, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Liu, ZD,Wang, DX,Xue, QM,et al. Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome[J]. NUTRITIONAL NEUROSCIENCE,2003,6(6):389-392.
APA	Liu, ZD.,Wang, DX.,Xue, QM.,Chen, J.,Li, YJ.,...&Chang, LW.(2003).Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome.NUTRITIONAL NEUROSCIENCE,6(6),389-392.
MLA	Liu, ZD,et al."Determination of fatty acid levels in erythrocyte membranes of patients with chronic fatigue syndrome".NUTRITIONAL NEUROSCIENCE 6.6(2003):389-392.