FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES

doi:10.3724/SP.J.1105.2011.11113

CORC > 化学研究所 > 中国科学院化学研究所

	FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES
	Shi Xudong 1; Sun Lei 2; Gan Zhihua 1
刊名	ACTA POLYMERICA SINICA
	2011-08-20
期号	8 页码:866-873
关键词	Polylactide Porous Microspheres Solvent Removal Rate
ISSN号	1000-3304
DOI	10.3724/SP.J.1105.2011.11113
英文摘要	Porous polylactide (PLA) microspheres were prepared by means of the modified double emulsion solvent evaporation. The organic solvents with different boiling points and aqueous solubility were used to prepare PLA microspheres with different porous structures. Microspheres prepared with methylene chloride, chloroform and toluene as solvents had the similar homogeneous porous structure. while those microspheres with ethyl acetate as solvent showed a hollow structure with a porous thin shell. The effects of solvent types on porous structure of microspheres were discussed. It was concluded that the removal rate of solvent plays the decisive role in determining the porous structure of microspheres. Accordingly, a formation mechanism of porous microspheres fabricated with different solvents was proposed.
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000294090300010
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/72867]
专题	中国科学院化学研究所
通讯作者	Shi Xudong
作者单位	1.Chinese Acad Sci, Inst Chem, CAS Key Lab Engn Plast, Beijing 100190, Peoples R China 2.Jishuitan Hosp, Beijing Inst Traumatol & Orthoped, Beijing 100035, Peoples R China
推荐引用方式 GB/T 7714	Shi Xudong,Sun Lei,Gan Zhihua. FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES[J]. ACTA POLYMERICA SINICA,2011(8):866-873.
APA	Shi Xudong,Sun Lei,&Gan Zhihua.(2011).FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES.ACTA POLYMERICA SINICA(8),866-873.
MLA	Shi Xudong,et al."FORMATION MECHANISM OF SOLVENT-INDUCED POROUS PLA MICROSPHERES".ACTA POLYMERICA SINICA .8(2011):866-873.