Highly enantioselective iridium-catalyzed hydrogenation of quinoline derivatives using chiral phosphinite H8-BINAPO

doi:10.1002/adsc.200505130

CORC > 化学研究所 > 中国科学院化学研究所

	Highly enantioselective iridium-catalyzed hydrogenation of quinoline derivatives using chiral phosphinite H8-BINAPO
	Lam, KH ; Xu, LJ ; Feng, LC ; Fan, QH ; Lam, FL ; Lo, WH ; Chan, ASC
刊名	ADVANCED SYNTHESIS & CATALYSIS
	2005-11-01
卷号	347 期号:14 页码:1755-1758
关键词	Asymmetric Hydrogenation Immobilization Iridium Phosphinite Ligands Poly(Ethylene Glycol) Dimethyl Ether Quinoline
ISSN号	1615-4150
DOI	10.1002/adsc.200505130
英文摘要	The chiral diphosphinite H8-BINAPO derived from H8-BINOL has been used in the Ir-catalyzed asymmetric hydrogenation of quinolines, and high enantioselectivity (up to 97% ee) was obtained. Immobilization of the iridium catalyst in poly(ethylene glycol) dimethyl ether (DMPEG) is also discussed. With DMPEG/hexane biphasic system, better enantioselectivities were obtained as compared to those observed in aprotic organic solvents.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000233483000004
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/55939]
专题	中国科学院化学研究所
通讯作者	Fan, QH
作者单位	1.Hong Kong Polytech Univ, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China 2.Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China 3.Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Lam, KH,Xu, LJ,Feng, LC,et al. Highly enantioselective iridium-catalyzed hydrogenation of quinoline derivatives using chiral phosphinite H8-BINAPO[J]. ADVANCED SYNTHESIS & CATALYSIS,2005,347(14):1755-1758.
APA	Lam, KH.,Xu, LJ.,Feng, LC.,Fan, QH.,Lam, FL.,...&Chan, ASC.(2005).Highly enantioselective iridium-catalyzed hydrogenation of quinoline derivatives using chiral phosphinite H8-BINAPO.ADVANCED SYNTHESIS & CATALYSIS,347(14),1755-1758.
MLA	Lam, KH,et al."Highly enantioselective iridium-catalyzed hydrogenation of quinoline derivatives using chiral phosphinite H8-BINAPO".ADVANCED SYNTHESIS & CATALYSIS 347.14(2005):1755-1758.