Hierarchical Biointerfaces Assembled by Leukocyte-Inspired Particles for Specifically Recognizing Cancer Cells

doi:10.1002/smll.201400215

CORC > 化学研究所 > 中国科学院化学研究所

	Hierarchical Biointerfaces Assembled by Leukocyte-Inspired Particles for Specifically Recognizing Cancer Cells
	Meng, Jingxin 1; Liu, Hongliang 1; Liu, Xueli 2,3; Yang, Gao 2,3; Zhang, Pengchao 2,3; Wang, Shutao 1; Jiang, Lei 2
刊名	SMALL
	2014-09-24
卷号	10 期号:18 页码:3735-3741
关键词	Cancer Cells Hierarchical Structures Structure-property Relationships Bioinspired Materials Specific Recognition
ISSN号	1613-6810
DOI	10.1002/smll.201400215
英文摘要	By mimicking certain biochemical and physical attributes of biological cells, bio-inspired particles have attracted great attention for potential biomedical applications based on cell-like biological functions. Inspired by leukocytes, hierarchical biointerfaces are designed and prepared based on specific molecules-modified leukocyte-inspired particles. These biointerfaces can efficiently recognize cancer cells from whole blood samples through the synergistic effect of molecular recognition and topographical interaction. Compared to flat, mono-micro or nano-biointerfaces, these micro/nano hierarchical biointerfaces are better able to promote specific recognition interactions, resulting in an enhanced cell-capture efficiency. It is anticipated that this study may provide promising guidance to develop new bio-inspired hierarchical biointerfaces for biomedical applications.
语种	英语
出版者	WILEY-V C H VERLAG GMBH
WOS记录号	WOS:000342687700020
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/49953]
专题	中国科学院化学研究所
通讯作者	Wang, Shutao
作者单位	1.Chinese Acad Sci, Tech Inst Phys & Chem, Lab Bioinspired Smart Interface Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, BNLMS, Key Lab Organ Solids, Inst Chem, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Meng, Jingxin,Liu, Hongliang,Liu, Xueli,et al. Hierarchical Biointerfaces Assembled by Leukocyte-Inspired Particles for Specifically Recognizing Cancer Cells[J]. SMALL,2014,10(18):3735-3741.
APA	Meng, Jingxin.,Liu, Hongliang.,Liu, Xueli.,Yang, Gao.,Zhang, Pengchao.,...&Jiang, Lei.(2014).Hierarchical Biointerfaces Assembled by Leukocyte-Inspired Particles for Specifically Recognizing Cancer Cells.SMALL,10(18),3735-3741.
MLA	Meng, Jingxin,et al."Hierarchical Biointerfaces Assembled by Leukocyte-Inspired Particles for Specifically Recognizing Cancer Cells".SMALL 10.18(2014):3735-3741.