Physical Gelation of Polypeptide-Polyelectrolyte-Polypeptide (ABA) Copolymer in Solution

doi:10.1021/ma300663p

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	Physical Gelation of Polypeptide-Polyelectrolyte-Polypeptide (ABA) Copolymer in Solution
	Zhang, Ran 1; Duan, Xiaozheng 1; Shi, Tongfei 1; Li, Hongfei 1; An, Lijia 1; Huang, Qingrong 2
刊名	MACROMOLECULES
	2012-08-14
卷号	45 期号:15 页码:6201-6209
ISSN号	0024-9297
DOI	10.1021/ma300663p
英文摘要	The gelation behavior of polypeptide-polyelectrolyte-polypeptide in solution is investigated by Monte Carlo techniques. It is found that different hydrogen bonding styles, parallel and antiparallel, provide a major influence on the sol-gel transition and the chain conformation. The antiparallel hydrogen bonding style favors the bridge conformation, while loop conformation has less structural limitation with parallel bonding. However, in the parallel style, polyelectrolyte blocks are aligned in the same side of beta-sheets, which induces more steric constrains and the electrostatic repulsion. Consequently, compared with the parallel bonding style, the sol-gel transition of antiparallel style occurs at lower hydrogen bonding energy and the dihedral angle theta of antiparallel beta-sheets is a little higher. The increase of charging fraction of polyelectrolyte blocks prompts the sol-gel transition of both bonding styles but causes an impact on the number of hydrogen bond and the dihedral angle, indicating a decrease in the structure integrity.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000307479100043
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/47957]
专题	中国科学院化学研究所
通讯作者	Shi, Tongfei
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Rutgers State Univ, Dept Food Sci, New Brunswick, NJ 08901 USA
推荐引用方式 GB/T 7714	Zhang, Ran,Duan, Xiaozheng,Shi, Tongfei,et al. Physical Gelation of Polypeptide-Polyelectrolyte-Polypeptide (ABA) Copolymer in Solution[J]. MACROMOLECULES,2012,45(15):6201-6209.
APA	Zhang, Ran,Duan, Xiaozheng,Shi, Tongfei,Li, Hongfei,An, Lijia,&Huang, Qingrong.(2012).Physical Gelation of Polypeptide-Polyelectrolyte-Polypeptide (ABA) Copolymer in Solution.MACROMOLECULES,45(15),6201-6209.
MLA	Zhang, Ran,et al."Physical Gelation of Polypeptide-Polyelectrolyte-Polypeptide (ABA) Copolymer in Solution".MACROMOLECULES 45.15(2012):6201-6209.