Synthesis and characterization of -amino acid-containing polyester: poly[(epsilon-caprolactone)-co-(serine lactone)]

doi:10.1002/pi.4334

CORC > 化学研究所 > 中国科学院化学研究所

	Synthesis and characterization of -amino acid-containing polyester: poly[(epsilon-caprolactone)-co-(serine lactone)]
	Wei, Ying 1,2; Li, Xiaoyuan 1; Jing, Xiabin 1; Chen, Xuesi 1; Huang, Yubin 1
刊名	POLYMER INTERNATIONAL
	2013-03-01
卷号	62 期号:3 页码:454-462
关键词	Polyesters Ring-opening Polymerization Serine N-trityl-l-serine-beta-lactone
ISSN号	0959-8103
DOI	10.1002/pi.4334
英文摘要	Novel polyesters, poly[(epsilon-caprolactone)-co-(N-trityl-L-serine--lactone)]s, were prepared by copolymerizing epsilon-caprolactone (CL) with N-trityl-L-serine--lactone (TSL) using ZnEt2 as the catalyst. The number-average molecular weights were determined which ranged from 2.7 x 104 to 4.9 x 104 Da with dispersity values ranging from 1.6 to 1.8. The structures of the copolymers were investigated by means of 1H NMR, 13C NMR and infrared spectroscopies, thermogravimetric analysis and differential scanning calorimetry. The results indicated that CL and TSL monomer units were randomly distributed within the copolymer backbone structures and the ratios of TSL to CL in the copolymers were close to those in the feeds. After removal of the trityl group under mild condition, a new polyester with side amino groups provided by serine units was obtained. L929 cell culturing test indicated good biocompatibility of the polyester with or without protective groups. (c) 2012 Society of Chemical Industry
语种	英语
出版者	WILEY-BLACKWELL
WOS记录号	WOS:000315167100017
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/46963]
专题	中国科学院化学研究所
通讯作者	Huang, Yubin
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Wei, Ying,Li, Xiaoyuan,Jing, Xiabin,et al. Synthesis and characterization of -amino acid-containing polyester: poly[(epsilon-caprolactone)-co-(serine lactone)][J]. POLYMER INTERNATIONAL,2013,62(3):454-462.
APA	Wei, Ying,Li, Xiaoyuan,Jing, Xiabin,Chen, Xuesi,&Huang, Yubin.(2013).Synthesis and characterization of -amino acid-containing polyester: poly[(epsilon-caprolactone)-co-(serine lactone)].POLYMER INTERNATIONAL,62(3),454-462.
MLA	Wei, Ying,et al."Synthesis and characterization of -amino acid-containing polyester: poly[(epsilon-caprolactone)-co-(serine lactone)]".POLYMER INTERNATIONAL 62.3(2013):454-462.