Zirconium-Based Nanoscale Metal-Organic Framework/Poly(epsilon-caprolactone) Mixed-Matrix Membranes as Effective Antimicrobials

doi:10.1021/acsami.7b15826

CORC > 化学研究所 > 中国科学院化学研究所

	Zirconium-Based Nanoscale Metal-Organic Framework/Poly(epsilon-caprolactone) Mixed-Matrix Membranes as Effective Antimicrobials
	Liu, Ming 1,2; Wang, Lei 1; Zheng, Xiaohua 1,2; Xie, Zhigang 1
刊名	ACS APPLIED MATERIALS & INTERFACES
	2017-11-29
卷号	9 期号:47 页码:41512-41520
关键词	Metal-organic Frameworks Zirconium Mixed-matrix Membranes Poly(Epsilon-caprolactone) Antimicrobial
ISSN号	1944-8244
DOI	10.1021/acsami.7b15826
英文摘要	Metal-organic framework (MOF)-polymer mixed-matrix membranes (MMMs) have shown their superior performance in gas separation. However, their biological application has not been well-explored yet. Herein, a series of zirconium-based MOF MMMs with high MOF loading and homogeneous composition have been prepared through a facile drawdown coating process. Poly(epsilon-caprolactone) (PCL) has been selected as a binder for its good biocompatibility and biodegradability. Zr-MOF nanoparticles, UiO-66, and MOF-525, have been utilized as "filler" because of their superior chemical stability, good biological safety, and versatile functions. Both UiO-66/PCL MMMs and MOF-525/PCL MMMs have a uniform appearance even at the highest loading of 50 wt % for UiO-66 and 30 wt % for MOF-525, respectively. The integrity of pore structures of UiO-66 within MMMs maintains well, which is evidenced by dye separation. All obtained MMMs possess good biocompatibility and mechanical property. Upon irradiation, MOF-525/PCL MMMs generate reactive oxygen species and serve as effective antibacterial photodynamic agents against Escherichia coli. This study offers an alternative system for forming homogeneous MOF/polymer MMMs and represents the first example of exploiting hybrid MMMs for biological applications.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000417005900049
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/45119]
专题	中国科学院化学研究所
通讯作者	Wang, Lei; Xie, Zhigang
作者单位	1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Polymer Phys & Chem, Changchun 130022, Jilin, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Liu, Ming,Wang, Lei,Zheng, Xiaohua,et al. Zirconium-Based Nanoscale Metal-Organic Framework/Poly(epsilon-caprolactone) Mixed-Matrix Membranes as Effective Antimicrobials[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(47):41512-41520.
APA	Liu, Ming,Wang, Lei,Zheng, Xiaohua,&Xie, Zhigang.(2017).Zirconium-Based Nanoscale Metal-Organic Framework/Poly(epsilon-caprolactone) Mixed-Matrix Membranes as Effective Antimicrobials.ACS APPLIED MATERIALS & INTERFACES,9(47),41512-41520.
MLA	Liu, Ming,et al."Zirconium-Based Nanoscale Metal-Organic Framework/Poly(epsilon-caprolactone) Mixed-Matrix Membranes as Effective Antimicrobials".ACS APPLIED MATERIALS & INTERFACES 9.47(2017):41512-41520.