Ultrasensitive Determination of Copper in Complex Biological Media Based on Modulation of Plasmonic Properties of Gold Nanorods

doi:10.1021/ac401789n

CORC > 化学研究所 > 中国科学院化学研究所

	Ultrasensitive Determination of Copper in Complex Biological Media Based on Modulation of Plasmonic Properties of Gold Nanorods
	Chen, Shenna 1; Zhao, Qian 1; Liu, Fang 1; Huang, Haowen 1; Wang, Linqian 2; Yi, Shoujun 1; Zeng, Yunlong 1; Chen, Yi 3
刊名	ANALYTICAL CHEMISTRY
	2013-10-01
卷号	85 期号:19 页码:9142-9147
ISSN号	0003-2700
DOI	10.1021/ac401789n
英文摘要	Accurate determination of copper in complex biological media such as cells is quite difficult, and an analytical strategy based on copper-modulated formation of core-shell gold nanorods is described. Selective and label-free sensing can be achieved by measuring the change in the localized surface plasmon resonance absorption. The technique can determine trace amounts of copper in human serum, urine, and red blood cells without or with minimal sample pretreatment. The Cu detection limits are 20.67 mu M in human serum, 0.193 mu M in human urine, and 3.09 X 10(-16) g in a single cell. The advantages of the technique are the high selectivity, simple or no sample pretreatment, and label free. Boasting a practical detection limit down to 2 IM, only 10(3) red blood cells are needed to conduct the analysis and the technique may be extended to the detection of trace amounts of copper in a single cell.
语种	英语
出版者	AMER CHEMICAL SOC
WOS记录号	WOS:000330017500037
内容类型	期刊论文
源URL	[http://ir.iccas.ac.cn/handle/121111/42124]
专题	中国科学院化学研究所
通讯作者	Huang, Haowen
作者单位	1.Hunan Univ Sci & Technol, Sch Chem & Chem Engn, Minist Educ, Lab Theoret Chem & Mol Simulat, Xiangtan, Hunan, Peoples R China 2.Cent S Univ, Xiangya Med Sch, Hunan Prov Tumor Hosp, Dept Lab,Affiliated Tumor Hosp, Changsha, Hunan, Peoples R China 3.Chinese Acad Sci, Inst Chem, Key Lab Analyt Chem Living Biosyst, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Chen, Shenna,Zhao, Qian,Liu, Fang,et al. Ultrasensitive Determination of Copper in Complex Biological Media Based on Modulation of Plasmonic Properties of Gold Nanorods[J]. ANALYTICAL CHEMISTRY,2013,85(19):9142-9147.
APA	Chen, Shenna.,Zhao, Qian.,Liu, Fang.,Huang, Haowen.,Wang, Linqian.,...&Chen, Yi.(2013).Ultrasensitive Determination of Copper in Complex Biological Media Based on Modulation of Plasmonic Properties of Gold Nanorods.ANALYTICAL CHEMISTRY,85(19),9142-9147.
MLA	Chen, Shenna,et al."Ultrasensitive Determination of Copper in Complex Biological Media Based on Modulation of Plasmonic Properties of Gold Nanorods".ANALYTICAL CHEMISTRY 85.19(2013):9142-9147.