H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation

	H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation
	Wang, Guihua ; Zhan, Dawei ; Li, Laixing ; Lei, Fumin ; Liu, Bohua ; Liu, Di ; Xiao, Haixia ; Feng, Youjun ; Li, Jing ; Yang, Baoan ; Yin, Zuohua ; Song, Xiaohui ; Zhu, Xiaojia ; Cong, Yanlong ; Pu, Juan ; Wang, Jian ; Liu, Jinhua ; Gao, George F. ; Zhu, Qingyu
刊名	JOURNAL OF GENERAL VIROLOGY ; Wang Guihua, Zhan Dawei,Li Laixing, Lei Fumin,Liu Bohua,Liu Di,Xiao Haixia, Feng Youjun,Li Jing,Yang Baoan, Yin Zuohua, Song Xiaohui, Zhu Xiaojia,Cong Yanlong,Pu Juan,Wang Jian,Liu Jinhua, Gao George F.,Zhu Qingyu.H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation.JOURNAL OF GENERAL VIROLOGY,2008,89(march):697-702
	2008-03-01
英文摘要	Highly pathogenic avian influenza H5N1 virus has swept west across the globe and caused serious debates on the roles of migratory birds in virus circulation since the first large-scale outbreak in migratory birds of Lake Qinghai, 2005. In May 2006, another outbreak struck Lake Qinghai and six novel strains were isolated. To elucidate these QH06 viruses, the six isolates were subjected to whole-genome sequencing. Phylogenetic analyses show that QH06 viruses are derived from the lineages of Lake Qinghai, 2005. Five of the six novel isolates are adjacent to the strain A/Cygnus olor/Croatia/1/05, and the last one is related to the strain A/duck/Novosibirsk/ 02/05, an isolate of the flyway. Antigenic analyses suggest that QH06 and QH05 viruses are similar to each other. These findings implicate that QH06 viruses of Lake Qinghai may travel back via migratory birds, though not ruling out the possibility of local circulation of viruses of Lake Qinghai.; Highly pathogenic avian influenza H5N1 virus has swept west across the globe and caused serious debates on the roles of migratory birds in virus circulation since the first large-scale outbreak in migratory birds of Lake Qinghai, 2005. In May 2006, another outbreak struck Lake Qinghai and six novel strains were isolated. To elucidate these QH06 viruses, the six isolates were subjected to whole-genome sequencing. Phylogenetic analyses show that QH06 viruses are derived from the lineages of Lake Qinghai, 2005. Five of the six novel isolates are adjacent to the strain A/Cygnus olor/Croatia/1/05, and the last one is related to the strain A/duck/Novosibirsk/ 02/05, an isolate of the flyway. Antigenic analyses suggest that QH06 and QH05 viruses are similar to each other. These findings implicate that QH06 viruses of Lake Qinghai may travel back via migratory birds, though not ruling out the possibility of local circulation of viruses of Lake Qinghai.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/1228]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wang, Guihua,Zhan, Dawei,Li, Laixing,et al. H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation[J]. JOURNAL OF GENERAL VIROLOGY, Wang Guihua, Zhan Dawei,Li Laixing, Lei Fumin,Liu Bohua,Liu Di,Xiao Haixia, Feng Youjun,Li Jing,Yang Baoan, Yin Zuohua, Song Xiaohui, Zhu Xiaojia,Cong Yanlong,Pu Juan,Wang Jian,Liu Jinhua, Gao George F.,Zhu Qingyu.H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation.JOURNAL OF GENERAL VIROLOGY,2008,89(march):697-702,2008.
APA	Wang, Guihua.,Zhan, Dawei.,Li, Laixing.,Lei, Fumin.,Liu, Bohua.,...&Zhu, Qingyu.(2008).H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation.JOURNAL OF GENERAL VIROLOGY.
MLA	Wang, Guihua,et al."H5N1 avian influenza re-emergence of Lake Communication Qinghai: phylogenetic and antigenic analyses of the newly isolated viruses and roles of migratory birds in virus circulation".JOURNAL OF GENERAL VIROLOGY (2008).