Computational probing protein-protein interactions targeting small molecules

	Computational probing protein-protein interactions targeting small molecules
	Wang, Yong-Cui ; Chen, Shi-Long ; Deng, Nai-Yang ; Wang, Yong
刊名	BIOINFORMATICS
	2016-01-15
英文摘要	Motivation: With the booming of interactome studies, a lot of interactions can be measured in a high throughput way and large scale datasets are available. It is becoming apparent that many different types of interactions can be potential drug targets. Compared with inhibition of a single protein, inhibition of protein-protein interaction (PPI) is promising to improve the specificity with fewer adverse side-effects. Also it greatly broadens the drug target search space, which makes the drug target discovery difficult. Computational methods are highly desired to efficiently provide candidates for further experiments and hold the promise to greatly accelerate the discovery of novel drug targets.
内容类型	期刊论文
源URL	[http://210.75.249.4/handle/363003/6500]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wang, Yong-Cui,Chen, Shi-Long,Deng, Nai-Yang,et al. Computational probing protein-protein interactions targeting small molecules[J]. BIOINFORMATICS,2016.
APA	Wang, Yong-Cui,Chen, Shi-Long,Deng, Nai-Yang,&Wang, Yong.(2016).Computational probing protein-protein interactions targeting small molecules.BIOINFORMATICS.
MLA	Wang, Yong-Cui,et al."Computational probing protein-protein interactions targeting small molecules".BIOINFORMATICS (2016).