Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging

doi:10.1016/j.pdpdt.2019.01.031

	Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging
	He, Pan 1,2; Huang, Tao 1; Fang, Cheng 1; Su, Song 1; Tian, Jie 3; Xia, XianMing 1; Li, Bo 1
刊名	PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
	2019-03-01
卷号	25 页码:417-420
关键词	Indocyanine green Fluorescence imaging Implantation metastasis Hepatocellular carcinoma
ISSN号	1572-1000
DOI	10.1016/j.pdpdt.2019.01.031
通讯作者	Xia, XianMing(xxm6202@126.com) ; Li, Bo(liboer2002@126.com)
英文摘要	Background/purpose: Intraoperative fluorescence imaging with indocyanine green (ICG) plays a significant role in the identification of hepatocellular carcinoma (HCC) during Hepatectomy. Despite that, few researchers have reported using ICG fluorescence imaging to detect extrahepatic metastases. Herein, we report the successful application of ICG fluorescence imaging in the detection of extrahepatic metastatic lesions from primary liver cancer. Methods: In two HCC patients, a near-infrared fluorescence imaging system was used to intraoperatively examine the abdominal cavity for implantation metastasis after hepatectomy of the primary tumor, following preoperative intravenous infusion with ICG. Results: In the first case, the abdominal cavity implantation metastasis exhibited intense fluorescence and clear boundaries of tumors during abdominal tumor resection, and there was no fluorescence in the resection margin. In the second case, a new lesion that was not detected by preoperative imaging examination was found in the omentum by ICG fluorescence imaging. Intraoperative rapid freezing pathology showed that it was an adenocarcinoma. Accordingly, we revised the tumor staging. Conclusion: ICG fluorescence imaging can not only detect intrahepatic metastases, but also extrahepatic metastases. Furthermore, it can help surgeons correct tumor staging during surgery.
资助项目	Scientific and technological strategic cooperation Foundation ; Peoples Government of luzhou city, China[2017LZXNYD-J07]
WOS关键词	RESECTION ; RECURRENCE
WOS研究方向	Oncology
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000465059600064
资助机构	Scientific and technological strategic cooperation Foundation ; Peoples Government of luzhou city, China
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/24930]
专题	中国科学院自动化研究所
通讯作者	Xia, XianMing; Li, Bo
作者单位	1.Southwest Med Univ, Affiliated Hosp, Dept Hepatobiliary Surg, Luzhou 646000, Peoples R China 2.Southwest Med Univ, Affiliated Hosp, Dept Anesthesiol, Luzhou 646000, Peoples R China 3.Chinese Acad Sci, Key Lab Mol Imaging, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	He, Pan,Huang, Tao,Fang, Cheng,et al. Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging[J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,2019,25:417-420.
APA	He, Pan.,Huang, Tao.,Fang, Cheng.,Su, Song.,Tian, Jie.,...&Li, Bo.(2019).Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging.PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY,25,417-420.
MLA	He, Pan,et al."Identification of extrahepatic metastasis of hepatocellular carcinoma using indocyanine green fluorescence imaging".PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY 25(2019):417-420.