Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions

doi:10.1017/S002531541700162X

CORC > 海洋研究所 > 中国科学院海洋研究所 > 海洋生态与环境科学重点实验室

	Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions
	Zhang, Libin 1; Feng, Qiming 1,2; Ding, Kui1,2 ; Sun, Lina 1; Huo, Da 1,2; Fang, Yan 3; Zhang, Tao1 ; Yang, Hongsheng1
刊名	JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM
	2018-12-01
卷号	98 期号:8 页码:2039-2048
关键词	Apostichopus japonicus respiratory tree hypoxia stress response metabolic pathway
ISSN号	0025-3154
DOI	10.1017/S002531541700162X
文献子类	Article; Proceedings Paper
英文摘要	The sea cucumber Apostichopus japonicus is a deposit-feeder and vital for marine benthic ecosystems. Hypoxia can influence the behaviour and even lead to massive mortality in A. japonicus in the wild. It is important to understand the molecular responses of A. japonicus when exposed to acute changes in dissolved oxygen (DO) concentration. In this study, RNA-seq provided a general overview of the gene expression profiles of the respiratory tree of A. japonicus exposed to DO of 8 mg l(-1) (DO8), 4 mg l(-1) (DO4) and 2 mg l(-1) (DO2) conditions. Differentially expressed genes (DEGs) screening with the NOISeq method identified 51, 59 and 61 DEGs according to the criteria of fold change >= 2 and divergence probability >= 0.8 in the comparisons of DO2 vs DO4, DO2 vs DO8 and DO4 vs DO8, respectively. Gene ontology analysis showed that 'cellular process' and 'binding' had the most enriched DEGs in the categories of 'biological process' and 'molecular function', respectively (catalytic activity also had the most enriched DEGs in the category of 'molecular function' based on the comparison of DO2 vs DO8), while 'cell' and 'cell part' had the most enriched DEGs in the category of 'cellular component'. The DEGs were mapped to 79, 81 and 104 pathways in the KEGG database, and 8, 29 and 16 pathways were significantly enriched, respectively. The DO-specific DEGs identified in this study of the respiratory tree are important targets for further research into the biochemical mechanisms involved in the response of the sea cucumber to changes in the DO concentration.
学科主题	Marine & Freshwater Biology
WOS研究方向	Marine & Freshwater Biology
语种	英语
出版者	CAMBRIDGE UNIV PRESS
WOS记录号	WOS:000454077300018
内容类型	期刊论文
源URL	[http://ir.qdio.ac.cn/handle/337002/157509]
专题	海洋研究所_海洋生态与环境科学重点实验室
作者单位	1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, 7 Nanhai Rd, Qingdao 266071, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China 4.Ludong Univ, Sch Agr, 186 Hongqizhong Rd, Yantai 264025, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Libin,Feng, Qiming,Ding, Kui,et al. Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions[J]. JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM,2018,98(8):2039-2048.
APA	Zhang, Libin.,Feng, Qiming.,Ding, Kui.,Sun, Lina.,Huo, Da.,...&Yang, Hongsheng.(2018).Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions.JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM,98(8),2039-2048.
MLA	Zhang, Libin,et al."Genome-wide analysis of gene expression profile in the respiratory tree of sea cucumber (Apostichopus japonicus) in response to hypoxia conditions".JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM 98.8(2018):2039-2048.