Bioaccumulation, oxidative stress, immune responses and immune-related genes expression in northern snakehead fish, Channa argus, exposure to waterborne selenium

doi:10.1007/s11033-018-4550-8

	Bioaccumulation, oxidative stress, immune responses and immune-related genes expression in northern snakehead fish, Channa argus, exposure to waterborne selenium
	Li, Muyang 1,2; Zhu, Xinming 1,2; Tian, Jiaxin 1,2; Liu, Ming 3; Wang, Guiqin 1,2
刊名	MOLECULAR BIOLOGY REPORTS
	2019-02-01
卷号	46 期号:1 页码:947-955
关键词	Channa argus Selenium Bioaccumulation Oxidative stress Immune responses
ISSN号	0301-4851
DOI	10.1007/s11033-018-4550-8
通讯作者	Wang, Guiqin(wgqjlau@163.com)
英文摘要	The objective of this study was to evaluate the toxic effects on bioaccumulation, oxidative stress, immune responses and immune-related genes expression of Channa argus exposed for 28days with waterborne selenium (0, 50, 100, 200, and 400 mu g/L). After 28days, the order of Se accumulation in tissues was kidney>liver>spleen>intestine>gill>muscle. Antioxidant parameters in liver and spleen of C. argus evidenced an oxidative stress condition in waterborne selenium. In addition, immunological parameters and immune-related gene expression were all enhanced with an increase in Se expose levels. Our results suggest that waterborne Se exposure can induce considerable Se accumulation, oxidative stress and immunotoxic effects on C. argus.
资助项目	National Natural Science Foundation of China[31372540] ; earmarked fund for Modern Agro-industry Technology Research System[CARS-46]
WOS关键词	NF-KAPPA-B ; RED-SEA BREAM ; SODIUM SELENITE ; PAGRUS-MAJOR ; GROWTH ; ACCUMULATION ; CADMIUM ; P65 ; ACTIVATION ; RESISTANCE
WOS研究方向	Biochemistry & Molecular Biology
语种	英语
出版者	SPRINGER
WOS记录号	WOS:000462022300092
资助机构	National Natural Science Foundation of China ; earmarked fund for Modern Agro-industry Technology Research System
内容类型	期刊论文
源URL	[http://ir.igsnrr.ac.cn/handle/311030/48659]
专题	中国科学院地理科学与资源研究所
通讯作者	Wang, Guiqin
作者单位	1.Jilin Agr Univ, Coll Anim Sci & Technol, Changchun 130118, Jilin, Peoples R China 2.Jilin Agr Univ, Jilin Prov Key Lab Anim Nutr & Feed Sci, Changchun 130118, Jilin, Peoples R China 3.Inst Geog Sci & Nat Resources Res, Beijing 100101, Peoples R China
推荐引用方式 GB/T 7714	Li, Muyang,Zhu, Xinming,Tian, Jiaxin,et al. Bioaccumulation, oxidative stress, immune responses and immune-related genes expression in northern snakehead fish, Channa argus, exposure to waterborne selenium[J]. MOLECULAR BIOLOGY REPORTS,2019,46(1):947-955.
APA	Li, Muyang,Zhu, Xinming,Tian, Jiaxin,Liu, Ming,&Wang, Guiqin.(2019).Bioaccumulation, oxidative stress, immune responses and immune-related genes expression in northern snakehead fish, Channa argus, exposure to waterborne selenium.MOLECULAR BIOLOGY REPORTS,46(1),947-955.
MLA	Li, Muyang,et al."Bioaccumulation, oxidative stress, immune responses and immune-related genes expression in northern snakehead fish, Channa argus, exposure to waterborne selenium".MOLECULAR BIOLOGY REPORTS 46.1(2019):947-955.