A hybrid fluorous monolithic capillary column with integrated nanoelectrospray ionization emitter for determination of perfluoroalkyl acids by nano-liquid chromatography-nanoelectrospray ionization-mass spectrometry/mass spectrometry

doi:10.1016/j.chroma.2016.02.025

	A hybrid fluorous monolithic capillary column with integrated nanoelectrospray ionization emitter for determination of perfluoroalkyl acids by nano-liquid chromatography-nanoelectrospray ionization-mass spectrometry/mass spectrometry
	Zhang, Haiyang 1,2; Ou, Junjie 1; Wei, Yinmao 2; Wang, Hongwei 1,3; Liu, Zhongshan 1,3; Zou, Hanfa 1
刊名	JOURNAL OF CHROMATOGRAPHY A
	2016-04-01
卷号	1440 页码:66-73
关键词	Hybrid Fluorous Monolith Capillary Liquid Chromatography Integrated Nanoelectrospray Ionization Emitter Perfluoroalkyl Acids
ISSN号	0021-9673
DOI	10.1016/j.chroma.2016.02.025
文献子类	Article
英文摘要	A hybrid fluorous monolithic column was simply prepared via photo-initiated free radical polymerization of an acrylopropyl polyhedral oligomeric silsesquioxane (acryl-POSS) and a perfluorous monomer (2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoroheptyl acrylate) in UV-transparent fused-silica capillaries within 5 min. The physical characterization of hybrid fluorous monolith, including scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy, mercury intrusion porosimetry (MIP) and nitrogen adsorption/desorption measurement was performed. Chromatographic performance was also evaluated by capillary liquid chromatography (cLC). Due to the fluorous-fluorous interaction between fluorous monolith and analytes, fluorobenzenes could well be separated, and the column efficiencies reached 86,600-92,500 plates/m at the velocity of 0.87 mm/s for alkylbenzenes and 51,900-76,000 plates/m at the velocity of 1.10 mm/s for fluorobenzenes. Meanwhile, an approach to integrate nanoelectrospray ionization (ESI) emitter with hybrid fluorous monolithic column was developed for quantitative determination of perfluoroalkyl acids by nanoHPLC-ESI-MS/MS. The integration design could minimize extracolumn volume, thus excluding undesirable peak broadening and improving separation performance. (C) 2016 Elsevier B.V. All rights reserved.
WOS关键词	POROUS POLYMER MONOLITHS ; POLYHEDRAL OLIGOMERIC SILSESQUIOXANE ; POLYFLUOROALKYL SUBSTANCES ; STATIONARY PHASES ; SMALL MOLECULES ; CLICK REACTION ; PERFORMANCE ; SILICA ; METHACRYLATE ; SEPARATION
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
语种	英语
出版者	ELSEVIER SCIENCE BV
WOS记录号	WOS:000372943400008
内容类型	期刊论文
源URL	[http://cas-ir.dicp.ac.cn/handle/321008/170678]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者	Ou, Junjie; Wei, Yinmao; Zou, Hanfa
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.NW Univ Xian, Coll Chem & Mat Sci, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Xian 710069, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Haiyang,Ou, Junjie,Wei, Yinmao,et al. A hybrid fluorous monolithic capillary column with integrated nanoelectrospray ionization emitter for determination of perfluoroalkyl acids by nano-liquid chromatography-nanoelectrospray ionization-mass spectrometry/mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2016,1440:66-73.
APA	Zhang, Haiyang,Ou, Junjie,Wei, Yinmao,Wang, Hongwei,Liu, Zhongshan,&Zou, Hanfa.(2016).A hybrid fluorous monolithic capillary column with integrated nanoelectrospray ionization emitter for determination of perfluoroalkyl acids by nano-liquid chromatography-nanoelectrospray ionization-mass spectrometry/mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1440,66-73.
MLA	Zhang, Haiyang,et al."A hybrid fluorous monolithic capillary column with integrated nanoelectrospray ionization emitter for determination of perfluoroalkyl acids by nano-liquid chromatography-nanoelectrospray ionization-mass spectrometry/mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1440(2016):66-73.