Air oxidation and rearrangement reactions of methyl(pyro)pheophorbide-a in the presence of lithium hydroxide

	Air oxidation and rearrangement reactions of methyl(pyro)pheophorbide-a in the presence of lithium hydroxide
	Li Jia-Zhu ; Liu Wan-Hui ; Li Fu-Guo ; Wang Jin-Jun ; Suo You-Rui ; Liu Yong-Jun
刊名	CHINESE JOURNAL OF ORGANIC CHEMISTRY
	2007-12-01
英文摘要	In the presence of lithium hydroxide, air oxidation and rearrangement reactions of methyl pheophorbide-a (1a) followed by acidification with hydrochloric acid and methylation with diazomethane to give a mixture including purpurin-7 trimethyl ester (2), purpurin-18 methyl ester (3), chlorine-p(6) trimethyl ester (4), geoporphyrin derivatives (5) and 3-epoxyvinyl-3-devinylpurpurin-18 ester (6) were performed. Methyl pyropheophorbide-a (1b) was oxidized in the same reaction as chlorin la followed by chromatography isolation to obtain methyl 13 2 -oxopyropheophorbide-a (7), 15-formylpurpurin-5 dimehyl ester (8), purpurin-18 methyl ester (3) and 3-epoxyvinyl-3-devinylpurpurin-18 ester (6), respectively. The structures of new chlorophyll derivatives 5, 6 and 8 were characterized by UV, IR, H-1 NMR spectra and elemental analysis. The possible mechanisms for the air oxidation and rearrangement reaction were tentatively proposed.
内容类型	期刊论文
源URL	[http://ir.nwipb.ac.cn/handle/363003/6866]
专题	西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li Jia-Zhu,Liu Wan-Hui,Li Fu-Guo,et al. Air oxidation and rearrangement reactions of methyl(pyro)pheophorbide-a in the presence of lithium hydroxide[J]. CHINESE JOURNAL OF ORGANIC CHEMISTRY,2007.
APA	Li Jia-Zhu,Liu Wan-Hui,Li Fu-Guo,Wang Jin-Jun,Suo You-Rui,&Liu Yong-Jun.(2007).Air oxidation and rearrangement reactions of methyl(pyro)pheophorbide-a in the presence of lithium hydroxide.CHINESE JOURNAL OF ORGANIC CHEMISTRY.
MLA	Li Jia-Zhu,et al."Air oxidation and rearrangement reactions of methyl(pyro)pheophorbide-a in the presence of lithium hydroxide".CHINESE JOURNAL OF ORGANIC CHEMISTRY (2007).