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	Small but influential: the role of micrornas on gene regulatory network and 3 ' utr evolution
	Zhang, Rui1,2,3; Su, Bing1,2
刊名	Journal of genetics and genomics
	2009
卷号	36期号:1页码:1-6
关键词	Mirna Gene expression Regulatory network 3 ' utr evolution
ISSN号	1673-8527
通讯作者	Su, bing(sub@mail.kiz.ac.cn)
英文摘要	Micrornas (mirnas) are endogenous similar to 22 nucleotide noncoding rnas that regulate the expression of complementary messenger rnas (mrnas). thousands of mirna genes have been found in diverse species, and many of them are highly conserved. with the mirna roles identified in nearly all aspects of biological processes, evidence is mounting that mirnas could represent a new layer of regulatory network, and their regulatory effect might be much more pervasive than previously suspected. here we focus on the post-transcriptional level gene regulation of mirnas in animals and review how the mirnas act to sustain and shape up the expression profiles of specific cell types; how the mirnas integrate into the existing gene regulatory networks; and how the mirnas influence the evolution of 3'utr of mammalian mrnas.
WOS关键词	EMBRYONIC STEM-CELLS ; MESSENGER-RNA ; EXPRESSION ; MOTIFS ; IMPACT ; ORGANIZATION ; TRANSLATION ; REPRESSION ; PRINCIPLES ; CIRCUITRY
WOS研究方向	Biochemistry & Molecular Biology ; Genetics & Heredity
WOS类目	Biochemistry & Molecular Biology ; Genetics & Heredity
语种	英语
出版者	SCIENCE PRESS
WOS记录号	WOS:000262749000001
内容类型	期刊论文
URI标识	http://www.corc.org.cn/handle/1471x/2394192
专题	中国科学院大学
通讯作者	Su, Bing
作者单位	1.Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Peoples R China 2.Chinese Acad Sci, Kunming Primate Res Ctr, Kunming 650223, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Rui,Su, Bing. Small but influential: the role of micrornas on gene regulatory network and 3 ' utr evolution[J]. Journal of genetics and genomics,2009,36(1):1-6.
APA	Zhang, Rui,&Su, Bing.(2009).Small but influential: the role of micrornas on gene regulatory network and 3 ' utr evolution.Journal of genetics and genomics,36(1),1-6.
MLA	Zhang, Rui,et al."Small but influential: the role of micrornas on gene regulatory network and 3 ' utr evolution".Journal of genetics and genomics 36.1(2009):1-6.

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