| Firing frequency maxima of fast-spiking neurons in human, monkey, and mouse neocortex | |
| Wang, Bo1,2,3,4; Ke, Wei1; Guang, Jing2,3,4; Chen, Guang2,3,4; Yin, Luping2,3,4; Deng, Suixin1; He, Quansheng1; Liu, Yaping1; He, Ting1; Zheng, Rui2,3,4 | |
| 刊名 | Frontiers in cellular neuroscience
 |
| 2016-10-18 | |
| 卷号 | 10页码:13 |
| 关键词 | Firing frequency Fast-spiking neuron Human Monkey Neocortex |
| ISSN号 | 1662-5102 |
| DOI | 10.3339/fncel.2016.00239 |
| 通讯作者 | Shu, yousheng(yousheng@bnu.edu.cn) |
| 英文摘要 | Cortical fast-spiking (fs) neurons generate high-frequency action potentials (aps) without apparent frequency accommodation, thus providing fast and precise inhibition. however, the maximal firing frequency that they can reach, particularly in primate neocortex, remains unclear. here, by recording in human, monkey, and mouse neocortical slices, we revealed that fs neurons in human association cortices (mostly temporal) could generate aps at a maximal mean frequency (f-mean) of 338 hz and a maximal instantaneous frequency (f-inst) of 453 hz, and they increase with age. the maximal firing frequency of fs neurons in the association cortices (frontal and temporal) of monkey was even higher (f-mean 450 hz, f-inst 611 hz), whereas in the association cortex (entorhinal) of mouse it was much lower (f-mean 215 hz, f-inst 342 hz). moreover, fs neurons in mouse primary visual cortex (v1) could fire at higher frequencies (f-mean 415 hz, f-inst 582 hz) than those in association cortex. we further validated our in vitro data by examining spikes of putative fs neurons in behaving monkey and mouse. together, our results demonstrate that the maximal firing frequency of fs neurons varies between species and cortical areas. |
| WOS关键词 | PREFRONTAL-CORTEX ; K+ CHANNELS ; IN-VIVO ; ELECTROPHYSIOLOGICAL PROPERTIES ; HIPPOCAMPAL INTERNEURONS ; INHIBITORY INTERNEURONS ; GABAERGIC INTERNEURONS ; SOMATOSENSORY CORTEX ; CORTICAL-NEURONS ; PYRAMIDAL CELLS |
| WOS研究方向 | Neurosciences & Neurology |
| WOS类目 | Neurosciences |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| WOS记录号 | WOS:000385456700001 |
| 内容类型 | 期刊论文 |
| URI标识 | http://www.corc.org.cn/handle/1471x/2374916 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Shu, Yousheng |
| 作者单位 | 1.Beijing Normal Univ, Collaborat Innovat Ctr Brain Sci, State Key Lab Cognit Neurosci & Learning, IDG McGovern Inst Brain Res,Sch Brain & Cognit Sc, Beijing, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Neurosci, Shanghai, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Biol Sci, State Key Lab Neurosci, Shanghai, Peoples R China 4.Univ Chinese Acad Sci, Shanghai, Peoples R China 5.Capital Med Univ, Beijing Sanbo Brain Hosp, Epilepsy Ctr, Dept Neurosurg,Brain Inst, Beijing, Peoples R China 6.Capital Med Univ, Beijing Sanbo Brain Hosp, Epilepsy Ctr, Dept Neurol, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Bo,Ke, Wei,Guang, Jing,et al. Firing frequency maxima of fast-spiking neurons in human, monkey, and mouse neocortex[J]. Frontiers in cellular neuroscience,2016,10:13. |
| APA | Wang, Bo.,Ke, Wei.,Guang, Jing.,Chen, Guang.,Yin, Luping.,...&Shu, Yousheng.(2016).Firing frequency maxima of fast-spiking neurons in human, monkey, and mouse neocortex.Frontiers in cellular neuroscience,10,13. |
| MLA | Wang, Bo,et al."Firing frequency maxima of fast-spiking neurons in human, monkey, and mouse neocortex".Frontiers in cellular neuroscience 10(2016):13. |
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